Table 3 Keypoints in the use of montelukast in preschool children with wheezing disorders
From: Update on leukotriene receptor antagonists in preschool children wheezing disorders
Evidences | Controversies |
|---|---|
Effectiveness in episodic (viral) wheeze | Effectiveness of intermittent use in severe recurrent wheeze |
Effectiveness in multi-trigger wheeze | Effectiveness of combined therapy with inhaled steroids in wheezing children |
Reduction of airway inflammation | Effectiveness in severe post-RSV bronchiolitis wheeze |
Excellent safety profile | Effectiveness in acute exacerbation |
Good compliance due to oral single administration | Selection criteria of subjects with wheezing to treat with monotherapy or combined therapyv with inhaled steroids |