Table 11 Drugs used for the treatment of hypertension in children and adolescents, which on the basis of their long half-life are administered once-a-day
From: Focus on prevention, diagnosis and treatment of hypertension in children and adolescents
Recommended Daily Dose (mg) | ||||
|---|---|---|---|---|
Body Weight (kg) | ||||
Class | Drug name | 10-25 | 25-40 | >40 |
Renin-Angiotensin-Aldosterone | ||||
System Blockers | ||||
AT1-receptor Blockers | Candesartan | 4-8 | 8-16 | 16-32 |
Irbesartan | 37-75 | 75-150 | 150-300 | |
Losartan | 12-25 | (25)-100 | (50)-100 | |
Olmesartan | (2.5)-10 | 5-20 | 20-40 | |
Valsartan | 20-40 | 40-80 | 80-160 | |
ACE -Inhibitors | Benazepril | 2.5-5.0 | 5.0-10 | 10-20[40] |
Fosinopril | 1.3-2.5 | 2.5-10 | 5.0-20[40] | |
Lisinopril | 2.5-10 | 5.0-20 | 10.30[40] | |
Quinapril | 2.5-5.0 | 5.0-10 | 10-20[40] | |
Ramipril | 1.3-2.5 | 2.5-10 | 5.0-20 | |
Beta-Blockers | Atenolol | 12-25 | 25-100 | 100-200 |
Bisoprolol | 1.2-2.5 | 2.5-5.0 | 5.0-10 | |
Metoprolol | 10-25 | 25-100 | 100-200 | |
Calcium Antagonists | Amlodipine | 2.5-5.0 | 5-10 | 10-20 |
Thiazide Diuretics | Chlorthalidone | 6-12 | 12-25 | 25-50 |
Hydrochlorothiazide | 6-12 | 12-25 | 25-50 | |