Table 3 Clinical features, laboratory findings and pituitary volume at 3-month assessment
From: Growth impairment in children with atrophic autoimmune thyroiditis and pituitary hyperplasia
Patients | Height, cm (SDS) | Pubertal Stage (B/G-P) | Clinical findings | TSH, mUI/ml | FT4, pmol/l | TPOAb, IU/ml | TGAb, IU/ml | IGF-1, ng/ml | PRL, uUI/ml | Pituitary volume, mm3 |
|---|---|---|---|---|---|---|---|---|---|---|
Patient 1 | 133.7 (-3.72) | B3P1 | Dry and thickened skin | 0.24 | 12.3 | NA | NA | NA | NA | NA |
Patient 2 | 131.6 (-1.83) | B2P2 | No symptoms | 7.2 | 11.7 | NA | NA | 148.3 | 91.1 | NA |
Patient 3 | 124.2 (-1.08) | B1P1 | No symptoms | 2.47 | 17.24 | NA | NA | NA | NA | NA |
Patient 4 | 135.8 (-1.74) | G1P1 | Sparse brittle hair, dry and thickened skin | 25.14 | 9.39 | 633.2 | 502.44 | 138 | 406.38 | NA |
Patient 5 | 154.2 (-1.27) | G2P2 | No symptoms | 2.4 | 13.12 | 68.8 | 9.5 | 195.3 | NA | NA |
Patient 6 | 117.6 (-2.21) | B1P1 | No symptoms | 0.54 | 11.19 | 58.1 | 19.8 | 195 | 85.1 | 198.7 |
Patient 7 | 122 (-1.48) | B1P1 | No symptoms | 2.11 | 12.48 | 160.4 | 202.6 | 146.1 | 57.44 | 184.5 |
Patient 8 | NA | NA | No symptoms | 2.01 | 14.6 | NA | NA | NA | NA | NA |
Patient 11 | 160 (-1.06) | NA | No symptoms | 0.2 | 15.4 | NA | NA | NA | NA | NA |
Patient 12 | 137.5 (-2.19) | NA | No symptoms | 2.04 | 17.1 | NA | NA | NA | NA | 440.4 |