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Table 4 Clinical features, laboratory findings and pituitary volume at 6-month assessment

From: Growth impairment in children with atrophic autoimmune thyroiditis and pituitary hyperplasia

Patients

Height, cm

(SDS)

Pubertal Stage

(B/G-P)

Clinical

findings

TSH,

mUI/ml

FT4,

pmol/l

TPOAb,

IU/ml

TGAb,

IU/ml

IGF-1,

ng/ml

PRL, uUI/ml

Pituitary volume, mm3

Patient 1

136.7 (-3.5)

B4P2

Dry and

thickened skin

0.2

17.37

NA

NA

NA

NA

NA

Patient 2

134.4 (-1.81)

B3P3

No symptoms

0.239

18.7

1755

291

182.2

89

287.0

Patient 4

139.1 (-1.5)

G1P1

No symptoms

0.4

14.9

371

323.2

146

NA

327.6

Patient 5

163.1 (-0.92)

G3P3

No symptoms

1.6

15.44

58.2

15.1

234.7

NA

171.6

Patient 6

122.1 (-1.69)

B1P1

No symptoms

1.12

19.3

48.1

21.8

195

110.63

NA

Patient 7

123.5 (-1.46)

B1P1

No symptoms

1.8

12.99

140.4

192.4

196.1

57.44

NA

Patient 11

163.5 (-0.73)

G5P5

No symptoms

1.66

15.8

NA

NA

NA

NA

563.16

Patient 12

140.8 (-2.01)

G4P3

No symptoms

6.42

12.9

NA

NA

NA

NA

NA

  1. TSH = thyroid stimulating hormone; FT4 = free thyroxine; TPOAb = thyroid peroxidase antibodies; TGAb = thyroglobulin antibodies; IGF-1 = insulin growth factor-1; PRL = prolactin; M = male; F = female; NA = not available