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Neonatology – Italian Society of Neonatology (SIN)

This section covers all aspects of neonatal and fetal health, disease, treatment, and outcomes.

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  1. Neonatal mortality remains a serious public health concern in developing countries including Ethiopia. Ethiopia is one of the countries with the highest neonatal mortality in Africa. However, there is limited ...

    Authors: Zemenu Tadesse Tessema and Getayeneh Antehunegn Tesema
    Citation: Italian Journal of Pediatrics 2020 46:138
    Content type: Research Published on:

  2. Coronavirus disease 2019 (COVID-19), a highly contagious viral disease has spread from Wuhan, Hubei Province, China to all over the world from its first recognition on December 2019. To date, only a few neonat...

    Authors: Setareh Sagheb, Ameneh Lamsehchi, Mohamadreza Jafary, Reza Atef-Yekta and Kourosh Sadeghi
    Citation: Italian Journal of Pediatrics 2020 46:137
    Content type: Case report Published on:

  3. Hirschsprung disease, the most important congenital colonic dysmotility in children results from neural crest migration, differentiation, proliferation, or apoptosis defects where the rearranged during transfe...

    Authors: Ingrid Anne Mandy Schierz, Marcello Cimador, Mario Giuffrè, Claudia Maria Aiello, Vincenzo Antona, Giovanni Corsello and Ettore Piro
    Citation: Italian Journal of Pediatrics 2020 46:135
    Content type: Case report Published on:

  5. Bleedings are more frequent in the population of preterm children than among those born at term, much less in older children. The reasons for such bleedings in preterms include plasma factor deficiencies, imma...

    Authors: Agnieszka Berendt, Monika Wójtowicz-Marzec, Barbara Wysokińska and Anna Kwaśniewska
    Citation: Italian Journal of Pediatrics 2020 46:125
    Content type: Case report Published on:

  6. Mothers in low socio-economic conditions frequently have low birth weight infants. Inaddition Physically demanding work during pregnancy also contributes to poor fetal growth. During gestation a woman needs ba...

    Authors: Sielu Alemayehu Desta, Ashenafi Damte and Tsehay Hailu
    Citation: Italian Journal of Pediatrics 2020 46:124
    Content type: Research Published on:

  7. Necrotizing enterocolitis (NEC) and supraventricular tachycardia (SVT) are serious emergencies in the neonatal period. Although these conditions are recognized as distinct pathologies, literature reports sugge...

    Authors: Federico Mecarini, Federica Comitini, Flaminia Bardanzellu, Paola Neroni and Vassilios Fanos
    Citation: Italian Journal of Pediatrics 2020 46:117
    Content type: Case report Published on:

  8. Transition from intrauterine to extrauterine life is a critical phase during which several changes occur in cardiovascular system. In clinical practice, it is important to have a method that allows an easy, ra...

    Authors: Daniela Doni, Silvia Nucera, Camilla Rigotti, Elena Arosio, Valeria Cavalleri, Monica Ronconi, Maria Luisa Ventura and Tiziana Fedeli
    Citation: Italian Journal of Pediatrics 2020 46:112
    Content type: Research Published on:

  9. Pregnancy may represent a time of exceptional vulnerability to intimate partner violence because of changes in women’s conditions. Despite the fact that intimate partner violence during pregnancy confers consi...

    Authors: Kahsay Zenebe Gebreslasie, Solomon Weldemariam, Gelawdiyos Gebre and Mihret-Ab Mehari
    Citation: Italian Journal of Pediatrics 2020 46:107
    Content type: Research Published on:

  10. Preterm infants have an increased risk of cognitive and behavioral deficits and cerebral palsy compared to term born babies. Especially before 32 weeks of gestation, infants may require respiratory support, bu...

    Authors: Laura Cannavò, Immacolata Rulli, Raffaele Falsaperla, Giovanni Corsello and Eloisa Gitto
    Citation: Italian Journal of Pediatrics 2020 46:100
    Content type: Review Published on:

  11. The Sudden Unexpected Infant Death Syndrome (SUID) is one of the leading causes of mortality in the first year of life. The aim of this work was the retrospective evaluation of the incidence of SUID and the ef...

    Authors: Raffaele Piumelli, Niccolò Nassi, Annamaria Buccoliero, Rossella Occhini, Vincenzo Nardini, Paolo Toti, Cristina Salvatori, Marta Peruzzi and Cinzia Arzilli
    Citation: Italian Journal of Pediatrics 2020 46:99
    Content type: Research Published on:

  12. Syndromic congenital heart disease accounts for 30% of cases and can be determined by genetic, environmental or multifactorial causes. In many cases the etiology remains uncertain. Many known genes are respons...

    Authors: Silvia Amodeo, Giuseppe Vitrano, Melania Guardino, Giuseppe Paci, Fulvio Corselli, Vincenzo Antona, Giuseppe Barrano, Monia Magliozzi, Antonio Novelli, Renato Venezia and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2020 46:98
    Content type: Case report Published on:

  13. Tracheal agenesis (TA) is a rare disorder usually diagnosed prenatally when a congenital high airway obstruction syndrome (CHAOS) is identified. We present a case of unexpected TA in a neonate without prenatal...

    Authors: Alessandro Perri, Maria Letizia Patti, Annamaria Sbordone, Giovanni Vento and Rita Luciano
    Citation: Italian Journal of Pediatrics 2020 46:96
    Content type: Case report Published on:

    The Correction to this article has been published in Italian Journal of Pediatrics 2020 46:115

  14. Linezolid is a synthetic antibiotic which is active against most Gram-positive bacteria, especially on Staphylococcus aureus. Its administration can be required when the infection is due to staphylococcus strains...

    Authors: Cinzia Auriti, Fiammetta Piersigilli, Iliana Bersani, Sara Cairoli, Paolina Giuseppina Amante, Daniela Longo and Bianca Maria Goffredo
    Citation: Italian Journal of Pediatrics 2020 46:90
    Content type: Case report Published on:

  15. Furosemide is approved in full term neonates to treat edema associated with congestive heart failure, cirrhosis and renal diseases. It is often administered off-label in premature neonates, to treat respirator...

    Authors: Valeria Anna Manfredini, Chiara Cerini, Antonio Clavenna, Andrea Dotta, Maria Letizia Caccamo, Alex Staffler, Luca Massenzi and Rossano Massimo Rezzonico
    Citation: Italian Journal of Pediatrics 2020 46:86
    Content type: Research Published on:

  16. Vitamin A administration may decrease any stage of retinopathy of prematurity (ROP) in preterm infants. To evaluate whether vitamin A oral supplementation could be preventive in ROP incidence and severity in V...

    Authors: Francesca Garofoli, Donatella Barillà, Micol Angelini, Iolanda Mazzucchelli, Annalisa De Silvestri, Rosanna Guagliano, Lidia Decembrino and Chryssoula Tzialla
    Citation: Italian Journal of Pediatrics 2020 46:77
    Content type: Letter to the Editor Published on:

  17. The rate of twinning continues to increase due to the combined effect of a rise in parental age and increased use of assisted reproductive technology. The risk of congenital anomalies in twins is higher than i...

    Authors: Ettore Piro, Ingrid Anne Mandy Schierz, Gregorio Serra, Giuseppe Puccio, Mario Giuffrè and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2020 46:73
    Content type: Research Published on:

  18. Delayed umbilical cord clamping is associated with greater haemoglobin concentration and iron storage between 3 and 6 months of life and with less need of blood transfusion and lower incidence of neonatal hypo...

    Authors: Giuseppe De Bernardo, Maurizio Giordano, Rita De Santis, Paola Castelli, Desiree Sordino, Daniele Trevisanuto, Giuseppe Buonocore and Serafina Perrone
    Citation: Italian Journal of Pediatrics 2020 46:71
    Content type: Research Published on:

  19. Human Immunodeficiency Virus (HIV) infection and low birth weight (LBW) continue to be significant public health concerns in many low-income countries including Ethiopia. Yet the effect of maternal HIV infecti...

    Authors: Andualem Zenebe, Betelhem Eshetu and Samson Gebremedhin
    Citation: Italian Journal of Pediatrics 2020 46:70
    Content type: Research Published on:

  20. A prompt diagnosis of HIE remains a challenge clinically. This study aimed to identify potential biomarkers of neonatal hypoxic-ischemic encephalopathy (HIE) via a novel proteomic approach, the isobaric tags f...

    Authors: Yuanyuan Zhu, Yajing Yun, Meifang Jin, Gen Li, Hong Li, Po Miao, Xin Ding, Xing Feng, Lixiao Xu and Bin Sun
    Citation: Italian Journal of Pediatrics 2020 46:67
    Content type: Research Published on:

  21. Recently, an outbreak of viral pneumonitis in Wuhan, Hubei, China successively spread as a global pandemia, led to the identification of a novel betacoronavirus species, the 2019 novel coronavirus, successivel...

    Authors: Domenico Umberto De Rose, Fiammetta Piersigilli, Maria Paola Ronchetti, Alessandra Santisi, Iliana Bersani, Andrea Dotta, Olivier Danhaive and Cinzia Auriti
    Citation: Italian Journal of Pediatrics 2020 46:56
    Content type: Review Published on:

  22. Although disseminated intravascular coagulation (DIC) is a critical disease, there is few gold standard interventions in neonatal medicine. The aim of this study is to reveal factors affecting neonatal DIC at ...

    Authors: Hayato Go, Hitoshi Ohto, Kenneth E. Nollet, Nozomi Kashiwabara, Kei Ogasawara, Mina Chishiki, Shun Hiruta, Ichiri Sakuma, Yukihiko Kawasaki and Mitsuaki Hosoya
    Citation: Italian Journal of Pediatrics 2020 46:54
    Content type: Research Published on:

  23. An early diagnosis of CHARGE syndrome is challenging, especially for the primary care physicians who often take care of neonates with multiple congenital anomalies. Here we report eight cases of CHARGE syndrom...

    Authors: Maria Francesca Bedeschi, Beatrice Letizia Crippa, Lorenzo Colombo, Martina Buscemi, Cesare Rossi, Roberta Villa, Silvana Gangi, Odoardo Picciolini, Claudia Cinnante, Viola Giulia Carlina Fergnani, Paola Francesca Ajmone, Elisa Scola, Fabio Triulzi and Fabio Mosca
    Citation: Italian Journal of Pediatrics 2020 46:53
    Content type: Research Published on:

  24. Feeding intolerance in premature infants is one of the main causes of their long-term hospitalization in NICUs. Massage therapy is a cost-effective intervention that has a positive impact on the health of infa...

    Authors: Leila Seiiedi-Biarag and Mojgan Mirghafourvand
    Citation: Italian Journal of Pediatrics 2020 46:52
    Content type: Review Published on:

  25. Exposure to hypothermia is somehow unavoidable when a baby comes to life. This is the reason why any possible effort should be made by every caregiver involved during birth, from labour to transfer into the ma...

    Authors: Daniele Merazzi, Ilia Bresesti, Paolo Tagliabue, Maria Grazia Valsecchi, Paola De Lorenzo and Gianluca Lista
    Citation: Italian Journal of Pediatrics 2020 46:46
    Content type: Research Published on:

  26. Fetal programming during in utero life defines the set point of physiological and metabolic responses that lead into adulthood; events happening in “the first 1,000 days” (from conception to 2-years of age), p...

    Authors: Benedetta Raspini, Debora Porri, Rachele De Giuseppe, Marcello Chieppa, Marina Liso, Rosa Maria Cerbo, Elisa Civardi, Francesca Garofoli, Maria Cristina Monti, Mirco Vacca, Maria De Angelis and Hellas Cena
    Citation: Italian Journal of Pediatrics 2020 46:45
    Content type: Research Published on:

  27. Harlequin Ichthyosis is the most severe variant of congenital autosomal recessive ichthyosis, associated with severe morbidity and potentially lethal in early life. At birth, patients present thick and plaque-...

    Authors: Cinzia Auriti, Roberta Rotunno, Andrea Diociaiuti, Silvia Magni Manzoni, Andrea Uva, Iliana Bersani, Alessandra Santisi, Andrea Dotta and May El Hachem
    Citation: Italian Journal of Pediatrics 2020 46:44
    Content type: Case report Published on:

  28. Preterm infants are at risk for structural disruption of brain connectivity due to perinatal complications encountered during the fetal and neonatal periods. This study aimed to investigate the development of ...

    Authors: Jong Ho Cha, Yong-Ho Choi, Jong-Min Lee, Joo Young Lee, Hyun-Kyung Park, Jinsup Kim, Il-Kewon Kim and Hyun Ju Lee
    Citation: Italian Journal of Pediatrics 2020 46:43
    Content type: Research Published on:

  29. In the last years, ‘omics’ technologies, and especially metabolomics, emerged as expanding scientific disciplines and promising technologies in the characterization of several pathophysiological processes.

    Authors: Flaminia Bardanzellu and Vassilios Fanos
    Citation: Italian Journal of Pediatrics 2020 46:37
    Content type: Review Published on:

  30. Healthcare-associated infections (HAIs) occur frequently in intensive care units (NICUs). The aim of this study was to analyze the results of surveillance of HAIs in a III level NICU in Naples, Italy during 20...

    Authors: Marina Silvia Scamardo, Pasquale Dolce, Eliana Pia Esposito, Francesco Raimondi, Maria Triassi and Raffaele Zarrilli
    Citation: Italian Journal of Pediatrics 2020 46:34
    Content type: Research Published on:

  31. Aplasia cutis congenita (ACC), classified in nine groups, is likely to be underreported, since milder isolated lesions in wellbeing newborns could often be undetected, and solitary lesions in the context of po...

    Authors: Ingrid Anne Mandy Schierz, Mario Giuffrè, Antonello Del Vecchio, Vincenzo Antona, Giovanni Corsello and Ettore Piro
    Citation: Italian Journal of Pediatrics 2020 46:25
    Content type: Research Published on:

  33. The optimal management of PDA in very low birth weight (VLBW) infants is still controversial. Aim of our study was to investigate the management of PDA in the Italian neonatal intensive care units (NICU).

    Authors: Benjamim Ficial, Iuri Corsini, Stefano Fiocchi, Federico Schena, Irma Capolupo, Rosa Maria Cerbo, Manuela Condò, Daniela Doni, Simona La Placa, Salvatore Porzio, Katia Rossi, Sabrina Salvadori and Marilena Savoia
    Citation: Italian Journal of Pediatrics 2020 46:22
    Content type: Research Published on:

  35. Neonatal acidaemia at birth can increase neonatal morbidity and mortality and it is predictive of neonatal asphyxia. The umbilical blood gas analysis is a valid tool for the evaluation of neonatal acidaemia. H...

    Authors: Giuseppe De Bernardo, Rita De Santis, Maurizio Giordano, Desiree Sordino, Giuseppe Buonocore and Serafina Perrone
    Citation: Italian Journal of Pediatrics 2020 46:20
    Content type: Research Published on:

  36. In recent years, medical training has significantly increased the use of simulation for teaching and evaluation. The retraining of medical personnel in Italy is entrusted to the program of Continuous Education...

    Authors: Alice Covelli, Serena Bardelli, Rosa T. Scaramuzzo, Emilio Sigali, Massimiliano Ciantelli, Marta Del Pistoia, Alessia Longo, Selene Tognarelli, Arianna Menciassi and Armando Cuttano
    Citation: Italian Journal of Pediatrics 2020 46:13
    Content type: Research Published on:

  37. Preterm birth (PTB) can be caused by different factors. The factors can be classified into different categories: socio demographic, obstetric, reproductive health, medical, behavioral and nutritional related. ...

    Authors: Tariku Laelago, Tadele Yohannes and Gulima Tsige
    Citation: Italian Journal of Pediatrics 2020 46:10
    Content type: Review Published on:

  38. In Italy live about 8.7% immigrants, which contribute to more than 15% of all deliveries taking place in Italy. We aimed to investigate whether newborns from high migratory pressure countries (HMPC) mothers ha...

    Authors: Mario De Curtis, Leonardo Villani and Arianna Polo
    Citation: Italian Journal of Pediatrics 2020 46:8
    Content type: Letter to the Editor Published on:

  39. Congenital cytomegalovirus (cCMV) infection is the most frequent non-genetic cause of sensorineural hearing-loss (SNHL) (i.e., hearing loss due to a cochlear and/or auditory nerve damage). It is widely accepte...

    Authors: Fabio Natale, Mario De Curtis, Bianca Bizzarri, Maria Patrizia Orlando, Massimo Ralli, Giuseppina Liuzzi, Barbara Caravale, Francesco Franco, Aurelia Gaeta, Antonella Giancotti, Francesca Yoshie Russo and Rosaria Turchetta
    Citation: Italian Journal of Pediatrics 2020 46:3
    Content type: Research Published on:

  40. Anemia in newborn babies causes asymptomatic to an acute life-threatening event. If untreated, it leads to a delay in brain maturation, tissue hypoxia, and stunted growth. In Sub-Saharan Africa, its burden ran...

    Authors: Tegenaw Tiruneh, Elias Shiferaw and Bamlaku Enawgaw
    Citation: Italian Journal of Pediatrics 2020 46:1
    Content type: Research Published on:

  41. Two hundred seventy-five thousand maternal deaths, 2.7 million neonatal deaths, and 2.6 million stillbirths have been estimated in 2015 worldwide, almost all in low-income countries (LICs). Moreover, more than...

    Authors: Gregorio Serra, Vincenzo Miceli, Salvatore Albano and Giovanni Corsello
    Citation: Italian Journal of Pediatrics 2019 45:152
    Content type: Research Published on:

  42. Neonatal sepsis is one of the leading causes of neonatal morbidity and mortality. Despite implementing of different preventive interventions, the burden of neonatal sepsis is reporting in different areas of Et...

    Authors: Mulunesh Alemu, Mulatu Ayana, Hailemariam Abiy, Biniam Minuye, Wubet Alebachew and Aklilu Endalamaw
    Citation: Italian Journal of Pediatrics 2019 45:150
    Content type: Research Published on:

  43. Birth weight and leptin seem to be the factors responsible for early programming of body weight in later life. A marker for leptin action is free leptin index (FLI), which depends on soluble leptin receptor (O...

    Authors: Beata Kulik-Rechberger, Anna Maria Bury, Anna Rakuś-Kwiatosz and Iwona Beń-Skowronek
    Citation: Italian Journal of Pediatrics 2019 45:141
    Content type: Research Published on:

  44. Preterm infants have immature gastrointestinal tracts and poor immunity. In this study, the effects of Lactobacillus reuteri DSM 17938 first on early feeding tolerance, growth, and second on infection prevention ...

    Authors: Xuewei Cui, Yongyan Shi, Siyang Gao, Xindong Xue and Jianhua Fu
    Citation: Italian Journal of Pediatrics 2019 45:140
    Content type: Research Published on:

  45. The only pharmacologic prophylaxis against respiratory syncytial virus (RSV) infection in preterm infants is the humanized monoclonal antibody palivizumab. After the 2014 modification of the American Academy o...

    Authors: Renato Cutrera, Andrea Wolfler, Simonetta Picone, Giovanni A. Rossi, Giuliana Gualberti, Rocco Merolla, Antonio Del Vecchio, Alberto Villani, Fabio Midulla and Andrea Dotta
    Citation: Italian Journal of Pediatrics 2019 45:139
    Content type: Review Published on:

  46. Neonatologist performed echocardiography (NPE) has increasingly been used to assess the hemodynamic status in neonates. Aim of this survey was to investigate the utilization of NPE in Italian neonatal intensiv...

    Authors: Iuri Corsini, Benjamim Ficial, Stefano Fiocchi, Federico Schena, Irma Capolupo, Rosa Maria Cerbo, Manuela Condò, Daniela Doni, Simona La Placa, Salvatore Porzio, Katia Rossi, Sabrina Salvadori and Marilena Savoia
    Citation: Italian Journal of Pediatrics 2019 45:131
    Content type: Research Published on:

  47. Melatonin has been studied and used for several years as a sleep-wake cycle modulator in patients with sleep disorders. Experimental evidence has demonstrated the multiple neuroprotective benefits of this indo...

    Authors: S. Picone, P. Ariganello, V. Mondì, F. Di Palma, L. Martini, S. Marziali, G. Fariello and P. Paolillo
    Citation: Italian Journal of Pediatrics 2019 45:122
    Content type: Research Published on:

  49. In this study, we aimed to analyze differences in plasma protein abundances between infants with and without bronchopulmonary dysplasia (BPD), to add new insights into a better understanding of the pathogenesi...

    Authors: Magdalena Zasada, Maciej Suski, Renata Bokiniec, Monika Szwarc-Duma, Maria Katarzyna Borszewska-Kornacka, Józef Madej, Beata Bujak-Giżycka, Anna Madetko-Talowska, Cecilie Revhaug, Lars O. Baumbusch, Ola D. Saugstad, Jacek Józef Pietrzyk and Przemko Kwinta
    Citation: Italian Journal of Pediatrics 2019 45:112
    Content type: Research Published on:

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Italian Journal of Pediatrics

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