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  1. Review

    Clinical practice recommendations for allergen-specific immunotherapy in children: the Italian consensus report

    Allergen-specific immunotherapy (AIT) is currently recognized as a clinically effective treatment for allergic diseases, with a unique disease-modifying effect. AIT was introduced in clinical practice one cent...

    Giovanni Battista Pajno, Roberto Bernardini, Diego Peroni, Stefania Arasi, Alberto Martelli, Massimo Landi, Giovanni Passalacqua, Antonella Muraro, Stefania La Grutta, Alessandro Fiocchi, Luciana Indinnimeo, Carlo Caffarelli, Elisabetta Calamelli, Pasquale Comberiati and Marzia Duse

    Italian Journal of Pediatrics 2017 43:13

    Published on: 23 January 2017

  2. Research

    Risk factors for Candida parapsilosis bloodstream infection in a neonatal intensive care unit: a case-control study

    Candida parapsilosis is increasingly responsible for invasive candidiasis in neonates. This study investigates phenotypic and genotypic features of C. parapsilosis microbial isolates a...

    Carmine Garzillo, Maria Bagattini, Lidija Bogdanović, Anna Di Popolo, Vita Dora Iula, Maria Rosaria Catania, Francesco Raimondi, Maria Triassi and Raffaele Zarrilli

    Italian Journal of Pediatrics 2017 43:10

    Published on: 19 January 2017

  3. Case report

    Management and long-term evolution of a patient with 3-hydroxy-3-methylglutaryl-coenzyme A lyase deficiency

    3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase deficiency is a rare inborn error of metabolism characterized by recurrent metabolic crises caused by fasting, intercurrent illness and excessive physical ...

    Juan Ignacio Muñoz-Bonet, María del Carmen Ortega-Sánchez and José Luis León Guijarro

    Italian Journal of Pediatrics 2017 43:12

    Published on: 19 January 2017

  4. Commentary

    Novel insight into Chronic Inflammatory Demyelinating Polineuropathy in APECED syndrome: molecular mechanisms and clinical implications in children

    Autoimmune polyendocrinopathy-candidiasis-ectodermal-dystrophy (APECED) is a rare primary immunodeficiency disorder typically caused by homozygous AIRE gene mutation. It is characterized by the association of mul...

    Mariella Valenzise, Tommaso Aversa, Giuseppina Salzano, Giuseppina Zirilli, Filippo De Luca and Maureen Su

    Italian Journal of Pediatrics 2017 43:11

    Published on: 19 January 2017

  5. Research

    Association of IL-10 gene polymorphisms and susceptibility to Juvenile Idiopathic Arthritis in Egyptian children and adolescents: a case-control study

    Juvenile Idiopathic Arthritis (JIA) is the most common chronic arthritis in children worldwide. Among anti-inflammatory cytokines, interleukin-10 (IL-10) is a key immunosuppressive cytokine involved in the pat...

    Manar M. Fathy, Hosam F. Elsaadany, Yasser F. Ali, Mohsen A. A. Farghaly, Mohammed E. Hamed, Hany E. Ibrahim, Maha A. Noah, Mayy A. N. Allah, Shaimaa S. A. Elashkar, Nasser I. Abdelsalam, Hind M. Abdelrahman, Ahmed R. Ahmed, Heba G. Anany, Sanaa M. Ismail, Boshra R. Ibrahim, Nashwa M. Al Azizi…

    Italian Journal of Pediatrics 2017 43:9

    Published on: 17 January 2017

  6. Review

    Ataxia in children: early recognition and clinical evaluation

    Ataxia is a sign of different disorders involving any level of the nervous system and consisting of impaired coordination of movement and balance. It is mainly caused by dysfunction of the complex circuitry co...

    Piero Pavone, Andrea D. Praticò, Vito Pavone, Riccardo Lubrano, Raffaele Falsaperla, Renata Rizzo and Martino Ruggieri

    Italian Journal of Pediatrics 2017 43:6

    Published on: 13 January 2017

  7. Research

    Sleep habits and pattern in 1-14 years old children and relationship with video devices use and evening and night child activities

    Sleep in childhood and adolescence is crucial for mental and physical health; however several researches reported an increasing trend towards a sleep deprivation in this age. Due to the lack of recent epidemio...

    Paolo Brambilla, Marco Giussani, Angela Pasinato, Leonello Venturelli, Francesco Privitera, Emanuele Miraglia del Giudice, Sara Sollai, Marina Picca, Giuseppe Di Mauro, Oliviero Bruni and Elena Chiappini

    Italian Journal of Pediatrics 2017 43:7

    Published on: 13 January 2017

  8. Research

    Rapid containment of nosocomial transmission of a rare community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) clone, responsible for the Staphylococcal Scalded Skin Syndrome (SSSS)

    The aims of this study were to identify the source and the transmission pathway for a Staphylococcal Scalded Skin Syndrome (SSSS) outbreak in a maternity setting in Italy over 2 months, during 2014; to impleme...

    Onofrio Lamanna, Dafne Bongiorno, Lisa Bertoncello, Stefano Grandesso, Sandra Mazzucato, Giovanni Battista Pozzan, Mario Cutrone, Michela Chirico, Flavia Baesso, Pierluigi Brugnaro, Viviana Cafiso, Stefania Stefani and Floriana Campanile

    Italian Journal of Pediatrics 2017 43:5

    Published on: 6 January 2017

  9. Research

    Computed tomography-guided biopsies in children: accuracy, efficiency and dose usage

    Computed-tomography-guided interventions are attractive for tissue sampling of paediatric tumor lesions; however, it comes with exposure to ionizing radiation. The aim of this study was to analyse the radiatio...

    Tatjana Gruber-Rouh, Axel Thalhammer, Thomas Klingebiel, Nour-Eldin A. Nour-Eldin, Thomas. J. Vogl, Katrin Eichler, Nagy Naguib and Martin Beeres

    Italian Journal of Pediatrics 2017 43:4

    Published on: 6 January 2017

  10. Research

    Percentiles of serum uric acid and cardiometabolic abnormalities in obese Italian children and adolescents

    To investigate the association of serum uric acid (SUA) with cardiometabolic abnormalities in Caucasian overweight/obese children (<10 years of age) versus adolescents (≥10 years of age) by drawing age and gen...

    Rosa Luciano, Blegina Shashaj, MariaRita Spreghini, Andrea Del Fattore, Carmela Rustico, Rita Wietrzykowska Sforza, Giuseppe Stefano Morino, Bruno Dallapiccola and Melania Manco

    Italian Journal of Pediatrics 2017 43:3

    Published on: 3 January 2017

  11. Commentary

    Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children

    Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is...

    Mariella Valenzise, Tommaso Aversa, Giuseppina Zirilli, Giuseppina Salzano, Domenico Corica, Simona Santucci and Filippo De Luca

    Italian Journal of Pediatrics 2017 43:2

    Published on: 3 January 2017

  12. Research

    Metabolic progression to clinical phenotype in classic Fabry disease

    Fabry disease is an X-linked lysosomal storage disorder due to α-galactosidase A (α-Gal A) deficiency. Clinical onset of Fabry disease is preceded by significant storage of globotriaosylceramide (Gb3) and rela...

    Marco Spada, David Kasper, Veronica Pagliardini, Elisa Biamino, Silvana Giachero and Francesco Porta

    Italian Journal of Pediatrics 2017 43:1

    Published on: 3 January 2017

  13. Research

    Vitamin D deficiency and its impact on asthma severity in asthmatic children

    Despite obtaining evidences on association between vitamin D and development of lung in fetus, little is known about vitamin D level and its impact on severity of asthma in children. The present study aimed to...

    Nasrin Esfandiar, Fariba Alaei, Shahrzad Fallah, Delara Babaie and Niloofar Sedghi

    Italian Journal of Pediatrics 2016 42:108

    Published on: 17 December 2016

  14. Research

    No effect of yeast-like fungi on lipid metabolism and vascular endothelial growth factor level in children and adolescents with type 1 diabetes mellitus

    The objective of the research was to investigate vascular endothelial growth factor (VEGF) levels in the context of lipid metabolism and amount of yeast-like fungi colonizing the digestive tract in children an...

    Katarzyna Zorena, Beata Kowalewska, Małgorzata Szmigiero-Kawko, Piotr Wąż and Małgorzata Myśliwiec

    Italian Journal of Pediatrics 2016 42:107

    Published on: 12 December 2016

  15. Research

    A randomized clinical trial comparing 3 different replacement regimens of vitamin D in clinically asymptomatic pediatrics and adolescents with vitamin D insufficiency

    Pediatric and Adolescent populations both have special needs for vitamin D especially for growing bone. Inadequate vitamin D is defined as 25 (OH) D(25hydroxy vitamin D) < 30 ng/ml.

    Iman M. Talaat, Naglaa M. Kamal, Hamed A. Alghamdi, Abdulla A. Alharthi and Mohamed A. Alshahrani

    Italian Journal of Pediatrics 2016 42:106

    Published on: 7 December 2016

  16. Case report

    Congenital cytomegalovirus related intestinal malrotation: a case report

    Cytomegalovirus is the most common cause of congenital infection in the developed countries. Gastrointestinal involvement has been extensively described in both adult and paediatric immunocompromised patients ...

    Claudia Colomba, Mario Giuffrè, Simona La Placa, Antonio Cascio, Marcello Trizzino, Simona De Grazia and Giovanni Corsello

    Italian Journal of Pediatrics 2016 42:105

    Published on: 7 December 2016

  17. Research

    Neonatal diffusion tensor brain imaging predicts later motor outcome in preterm neonates with white matter abnormalities

    White matter (WM) abnormalities associated with prematurity are one of the most important causes of neurological disability that involves spastic motor deficits in preterm newborns. This study aimed to evaluat...

    Do-yeon Kim, Hyun-Kyung Park, Nam-Su Kim, Se-Jin Hwang and Hyun Ju Lee

    Italian Journal of Pediatrics 2016 42:104

    Published on: 1 December 2016

  18. Review

    Physiopathology of vesico-ureteral reflux

    Vescico-Ureteral Reflux (VUR) is a common condition in childhood, caused by a congenital anomaly at the Vescico-Ureteral Junction (VUJ) level. It seems that the main cause could be an abnormal embryological de...

    Salvatore Arena, Roberta Iacona, Pietro Impellizzeri, Tiziana Russo, Lucia Marseglia, Eloisa Gitto and Carmelo Romeo

    Italian Journal of Pediatrics 2016 42:103

    Published on: 29 November 2016

  19. Research

    Genetic and epigenetic alterations in the GNAS locus and clinical consequences in Pseudohypoparathyroidism: Italian common healthcare pathways adoption

    Genetic and epigenetic alterations in the GNAS locus are responsible for the Gsα protein dysfunctions causing Pseudohypoparathyroidism (PHP) type Ia/c and Ib, respectively. For these heterogeneous diseases charac...

    L. de Sanctis, F. Giachero, G. Mantovani, G. Weber, M. Salerno, G. I. Baroncelli, F. M. Elli, P. Matarazzo, M. Wasniewska, L. Mazzanti, G. Scirè and D. Tessaris

    Italian Journal of Pediatrics 2016 42:101

    Published on: 21 November 2016

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Società Italiana di Pediatria

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