Table 1 Clinical characteristics of the study population
All (n = 13) | Children (n = 8) | Adults (n = 5) | |
|---|---|---|---|
Clinical data | |||
Male/Female | 9/4 | 6/2 | 3/2 |
Situs viscerum inversus (%) | 61 | 75 | 40 |
Age at study entry (yrs) | 15.2 (10.4–29.3) | 13.1 (10.4–17.7) | 23.8 (20.9–29.3) |
Age at onset of respiratory symptoms (yrs) | 0.1 (0.1–4) | 0.1 (0.1–4) | 0.1 (0.1–1) |
Presenting respiratory symptoms | |||
Chronic cough (%) | 46 | 50 | 40 |
Pneumonia (%) | 31 | 12.5 | 60 |
Persistent wheezing (%) | 8 | 12.5 | 0 |
Neonatal respiratory distress (%) | 15 | 25 | 0 |
Age at PCD diagnosis (yrs) | 7.3 (0.1–17.1) | 7 (0.3–15.5) | 10.1 (0.1–17.1) |
Exhaled nitric oxide (ppb) | 4.3 (1.5–8.2) | 5 (2.6–8.2) | 3.9 (1.5–6.9) |
Nasal nitric oxide (ppb) | 15.8 (2.6–34.3) | 12 (4.4–34.3) | 16.9 (2.6–30.1) |
Atopy (%) | 23 | 25 | 20 |
Lobectomy or segmentectomy (%) | 31 | 12 | 60 |