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Table 2 Conditioning regimen

From: High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome

 

Pre-conditioning

(-45 to -12)

Conditioning

(-11 to -2)

B-thal/Class 2

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iv Bu§ Cy 200 mg/kg

B-thal/Class 3

AZ/HU

Fludarabine 150 mg/m2

iv Bu§ Cy 160 mg/kg

ATG 7.5 mg/kg

SCD

AZ/HU

Fludarabine 150 mg/m2

iv Bu§ Cy 200 mg/kg

ATG 10 mg/kg