Figure 2From: "Idiopathic" mental retardation and new chromosomal abnormalitiesPictures of three patients with mental retardation and dysmorphisms with a genetic diagnosis. a) de novo 1p36 deletion in a 22 months old girl; b) The same patient at 3 years of age. Note prominent forehead, very straight eyebrows, epicanthus, deep-set eyes, flat nasal bridge, and thin lips; c) de novo 2q37.1 deletion in a 7 years old girl. Note bushy eyebrows, horizontal palpebral fissures, flat nasal philtrum with prominent columella, thin upper lip, high palate, microretrognatia, and rather asymmetrical ears; d) 22q11.2 duplication inherited from affected mother, in a 4 years old girl. Note high forehead, sparse eyebrows, short and downslanting palpebral fissures, hypertelorism, bulbous nose, pronounced philtrum, fullness of jowls, and large and simplified ears with protruding lobes.Back to article page