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Table 4 Serum levels of VEGF, PD-ECGF/TP activity and leptin in patients groups in relation to age, weight, hemoglobin and SpO2 levels.

From: Angiogenic biomarkers in children with congenital heart disease: possible implications

Biomarkers VEGF (pg/ml) PD-ECGF (U/ml) Leptin (ng/ml)
Patients groups   C-CHD (n = 30) A-CHD (n = 30) C-CHD (n = 30) A-CHD (n = 30) C-CHD (n = 30) A-CHD (n = 30)
  <3 ys (n = 39) 265 ± 100 296 ± 79 29 ± 7 20 ± 10.2 39 ± 12 32 ± 10
Age
(years)
        
  >3 ys (n = 21) 574 ± 92* 310 ± 91§ 34 ± 9.3§ 27 ± 6§ 43 ± 6.5§ 33.6 ± 5.9§
  <10 Kg (n = 34) 400 ± 96 306 ± 74 28.6 ± 7.8 25 ± 4.9 22 ± 4.9 20.9 ± 8.9
Weight
(Kg)
        
  >10 Kg (n = 26) 413 ± 78§ 327 ± 36§ 33 ± 6.4§ 30 ± 6.7§ 43 ± 10† 45.3 ± 9†
  <10 gm/dl (n = 32) 275 ± 102 300.5 ± 90 18.4 ± 6.4 21.2 ± 7.3 41 ± 7.9 31 ± 4.8
Hemoglobin
(g./dl)
        
  >10 gm/dl (n = 28) 567 ± 95* 313.2 ± 76§ 39 ± 9.6† 24.9 ± 6§ 43.8 ± 8§ 33.7 ± 5.6§
  <90% (n = 35) 582 ± 98 408 ± 59.2 48.3 ± 7.8 33 ± 5.4 49 ± 12 46.8 ± 9.5
SpO2
(%)
        
  >90% (n = 25) 206 ± 39* 210 ± 65.4* 27 ± 9.6† 18 ± 6.9† 27.8 ± 10.8‡ 22 ± 6.2 ‡
  1. *: p < 0.001
  2. †: p < 0.01
  3. ‡: p < 0.05
  4. §: not significant