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Table 2 Strategy, IgE results, physician's diagnosis, prevalences, frequencies, probabilities and costs in the twelve possible diagnostics categories, a1 to a12.

From: Health-care cost reduction resulting from primary-care allergy testing in children in Italy

Category (no. obs) Strategy Initial IgE test Physcian's diagnosis 1Prevalence Observed frequence 2Probability (p) 3Expected category cost (€)
         year 1 4year 2 year 1&2
a1 (9) no-test pos uncertain 0,55 0,09 0,050 24 23 47
a2 (79) no-test pos allergy 0,55 0,81 0,446 192 186 377
a3 (10) no-test pos no-allergy 0,55 0,10 0,055 26 25 52
a4 (21) no-test neg uncertain 0,45 0,22 0,099 48 46 94
a5 (54) no-test neg allergy 0,45 0,56 0,252 105 102 206
a6 (21) no-test neg no-allergy 0,45 0,22 0,099 13 13 26
a7 (1) test pos uncertain 0,55 0,01 0,006 1 0 1
a8 (87) test pos allergy 0,55 0,95 0,523 232 175 408
a9 (4) test pos no-allergy 0,55 0,04 0,022 12 9 21
a10 (3) test neg uncertain 0,45 0,05 0,023 12 12 24
a11 (10) test neg allergy 0,45 0,17 0,077 6 5 10
a12 (45) test neg no-allergy 0,45 0,78 0,351 51 46 97
  1. 1frequence of positive results during screening, i.e. positive results in Phadiatop/Padiatop Infant
  2. 2calculated from the prevalence and observed frequence of being in category
  3. 3calculated as the sum of costs for medications, physician visits and allergy tests adjusted for observed episodes per patient on pathway as given in Table 1 and probability of being in category.
  4. 4costs in 2nd year were discounted to correspond to 1st year (rate:3%)