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Table 1 Clinical, biochemical, and histological features of autoimmune hepatitis at presentation

From: HLA-DRB1 as a risk factor in children with autoimmune hepatitis and its relation to hepatitis A infection

Sex (F/M)

17/8

Type 1/type 2/seronegative AIH

17/5/3

Presentation:

 

   Acute

16 (64%)

   Chronic

9 (36%)

ALT(IU/L) × normal

10 × n

AST(IU/L) × normal

9 × n

Alb(g/dL)

3.5 ± 0.8

Gammaglobulin (g/dl)

3.3 ± 1.8

Total Bilirubin (mg/dl)

4.9 ± 2.8

Direct bilirubin (mg/dl)

3.1 ±1.95

ANA

9(36%)

ASMA

17 (68% )

Anti-LKM

5(20%)

Autoimmune thyroiditis ( 20)

3(15%)

Hepatitis A IgM +ve

6 (24%)

Liver biopsy:

 

   Interface hepatitis

23(92% )

Fibrosis

18 (72%)

Cirrhosis

7(32%)

Complete response

16(64%)

Partial response

7(28%)

Treatment failure

0

Non compliance

2(8%)