Table 4 Senna
From: Constipation in children
Authors | Study Group+ type | Methods+ Key Outcomes |
|---|---|---|
Berg (1983) [71] | 44 children with soiling (mean age 7.9 years) Study type 2b All given toileting advice. | RCT: senna vs. placebo vs. no treatment. Results: All groups improved from baseline (p < 0.05). Senna no more effective than placebo/no treatment. |
Perkin (1977) [53]- Study described in the 'Lactulose section' - table | ||
Sondheimer et al (1982) [72] | 37 children Study type: 2b | Methods: Non-blinded RCT Senna vs. mineral oil for 3 months Results: Faecal soiling + decreased stool frequency) significantly better in mineral-oil group. At least 1 recurrence of symptoms occurred in 66% of mineral-oil-treated and 89% of Senna-treated patients. |
Connolly et al (1974) [56] -Study described in the 'Lactulose section' - table | ||