|Authors||Study Group+ type||Methods+ Key Outcomes|
|Berg (1983) ||
44 children with soiling (mean age 7.9 years)|
Study type 2b
All given toileting advice.
RCT: senna vs. placebo vs. no treatment.|
Results: All groups improved from baseline (p < 0.05). Senna no more effective than placebo/no treatment.
|Perkin (1977) - Study described in the 'Lactulose section' - table|
|Sondheimer et al (1982) ||
Study type: 2b
Methods: Non-blinded RCT Senna vs. mineral oil for 3 months|
Results: Faecal soiling + decreased stool frequency) significantly better in mineral-oil group. At least 1 recurrence of symptoms occurred in 66% of mineral-oil-treated and 89% of Senna-treated patients.
|Connolly et al (1974)  -Study described in the 'Lactulose section' - table|