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Table 2 Symptoms, signs and orphan status in HIV positive and negative subjects

From: Prevalence and clinical pattern of paediatric HIV infection at the University College Hospital, Ibadan, Nigeria: a prospective cross-sectional study

 

HIV Status

    
 

Infected

(n = 60)

Uninfected

(n = 540)

Total

N = 600

OR (95% CI)

P

 

No.

%

No.

%

No.

%

  

Symptom

        

Fever

45

75.0

310

57.4

355

59.2

2.23(1.21,4.10)

0.008

Cough

39

65.0

128

23.7

167

27.8

5.98(3.39,10.53)

0.000

Fast breathing

8

1.3

82

15.2

90

15.0

0.86(0.39,1.88)

0.849

Diarrhoea

24

40.0

57

10.6

81

13.5

5.65(3.15,10.14)

0.000

Weight loss/falter

25

41.7

63

11.7

88

14.7

5.41(3.04,9.62)

0.000

Seizures

2

3.3

106

19.6

108

18.0

0.14(0.03,0.59)

0.001

Coma

-

-

21

3.9

21

3.5

-

0.254

Chronic diarrhoea

7

11.7

1

1.9

8

1.3

71.19(8.60,589.65)

0.000

Recurrent otorrohea

11

18.3

11

2.0

22

3.7

10.80(4.45,26.17)

0.000

Signs

        

Pallor

20

33.3

150

27.8

170

28.3

1.30 (0.74,2.30)

0.368

Jaundice

2

3.3

74

13.7

76

12.7

0.22 (0.05,0.91)

0.022

Oral thrush

8

13.3

8

1.5

16

2.7

10.23 (3.69,28.4)

0.000

Lymphadenopathy

33

55.0

33

6.1

66

11.0

18.78 (10.12,34.86)

0.000

Parotid fullness

13

21.7

3

0.6

16

2.7

49.51(13.63,179.92)

0.000

Otorrhoea

7

11.7

6

1.1

13

2.2

11.76 (3.81,36.26)

0.000

Skin lesions

24

40.0

32

5.9

56

9.3

10.58 (5.65,19.83)

0.000

Hepatomegaly

43

71.7

236

43.7

279

46.5

3.26 (1.81,5.86)

0.000

Splenomegaly

19

31.7

66

12.2

85

14.2

3.33 (1.82,6.08)

0.000

  1. Persistent fever: Unexplained fever (intermittent or constant) lasting ≥ 1 month, Chronic diarrhoea: At least two loose stools per day for ≥ 30 days, Recurrent otorrhoea: ≥ 2 episodes of ear discharge from the same ear