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Table 1 Baseline clinical and laboratory data of patients and control group.

From: Obesity modulate serum hepcidin and treatment outcome of iron deficiency anemia in children: A case control study

 

Obese children with IDA

Non obese children with IDA

Control

P

 

(n = 35)

(n = 35)

(n = 30)

 

Age (years)

6.96 ± 2.2

7.11 ± 2.57

7.11 ± 2.57

>0.05

Male/female #

22/18

23/17

11/9

>0.05

BMI (kg/m2)

25.70 ± 2.2 a

16.30 ± 1.9 b

16.2 ± 1.7 b

<0.05

Hb (g/dl)

8.82 ± 1.2 a

8.22 ± 1.4 a

13.0 ± 1.4 b

<0.05

MCV (fl)

70.80 ±4.6 a

69.33 ± 4.0 a

92.33 ± 7.0 b

<0.05

MCHC (%)

26.3 ± 2.3 a

25.6 ± 2.5 a

33.7 ± 2.6 b

<0.05

Serum iron (ug/dl)

28.83 ± 2.5 a

29.28 ± 4.6 a

90.45 ± 4.4 b

<0.05

TIBC (mg/dl)

491 ± 24 a

478 ± 15 a

258 ± 15 b

<0.05

Transferrin saturation (%)

5.87 ± 0.9 a

6.13 ± 1.2 a

35.05 ± 1.7 b

<0.05

Transferrin (umol/L)

75 ± 7.1 a

77 ± 6.8 a

34 ± 2.3 b

<0.05

Ferritin (ng/ml)

51.91 ± 8.7 a

7.52 ± 1.6 b

56.19 ± 4.1 a

<0.05

CRP (mg/dl)

5.71 ± 0.7 a

2.42 ± 0.5 b

2.53 ± 0.6 b

<0.05

Serum hepcidin (nmol/l)

4.96 ± 1.2 a

0.11 ± 0.03 b

1.61 ± 0.7 c

<0.05

  1. The P value is for ANOVA. a, b and c on means refer to significant difference between means when ANOVA test refers to significances by multiple comparison analysis (aa, bb, cc = non-significant, ab, ac, bc = significant). # Chi-square test.