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Table 1 Clinical and laboratory data in patients and controls

From: Urinary hepcidin level as an early predictor of iron deficiency in children: A case control study

  Control (n = 25) (Stage-1 ID) (n = 25) (Stage-2 ID) (n = 25) (Stage-3 ID) (n = 25) P
Age (year) 5.0 ± 0.9 5.1 ± 1.2 5.2 ± 1.3 4.9 ± 1.2 > 0.05
Male/female * 14/11 14/11 13/12 14/11 > 0.05
Body weight (kg) 17.2 ± 2.2 16.7 ± 2.3 16.0 ± 3.1 16.4 ± 2.6 > 0.05
Hb (g/dl) 12.5 ± 0.6a 11.9 ± 1.1a 11.8 ± 1.2a 7.9 ± 1.2b < 0.05
Hematocrit (%) 37.6 ± 2.1a 35.8 ± 2.4a 35.5 ± 1.5a 23.6 ± 2.1b < 0.05
MCV (fl) 92.3 ± 7.0a 87.8 ± 5.1a 86.8 ± 4.6a 61.1 ± 3.1b < 0.05
MCHC (%) 34.1 ± 2.6a 34.0 ± 2.1a 33.9 ± 2.3a 26.1 ± 2.4b < 0.05
Serum iron (ug/dl) 95.1 ± 4.6a 89.8 ± 2.5a 55.8 ± 2.5b 20.6 ± 1.1c < 0.05
TIBC(mg/dl) 264 ± 15a 254 ± 34a 391 ± 24b 483 ± 21c < 0.05
Tsat (%) 36.0 ± 1.1a 35.4 ± 0.6a 14.3 ± 0.9b 4.3 ± 0.6c < 0.05
Transferrin (umol/L) 34 ± 2.3a 36 ± 2.5a 35 ± 3.4a 76.2 ± 13.6b < 0.05
Ferritin (ng/ml) 69.2 ± 4.1a 16.0 ± 1.6b 10.5 ± 1.3c 5.3 ± 1.1d < 0.05
ZnPP (ug/dl) 27 ± 1.3a 28 ± 2.3a 129 ± 10.1b 134 ± 12.3b < 0.01
Urinary hepcidin-25 (nmol/mmol Cr) 2.8 ± 1.3a 0.7 ± 0.22b 0.3 ± 0.09c .079 ± .009d < 0.01
  1. The P value is for the difference between all groups by ANOVA test. aa, bb = non-significant (p > 0.05). ab, ac, ad = significant (P < 0.05). bc, bd, cd = significant (P < 0.05). *Chi-square test. Tsat = Transferrin saturation, ZnPP = erythrocyte zinc protoporphyrin.