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Table 1 Clinical and laboratory data in patients and controls

From: Urinary hepcidin level as an early predictor of iron deficiency in children: A case control study

 

Control

(n = 25)

(Stage-1 ID) (n = 25)

(Stage-2 ID) (n = 25)

(Stage-3 ID) (n = 25)

P

Age (year)

5.0 ± 0.9

5.1 ± 1.2

5.2 ± 1.3

4.9 ± 1.2

> 0.05

Male/female *

14/11

14/11

13/12

14/11

> 0.05

Body weight (kg)

17.2 ± 2.2

16.7 ± 2.3

16.0 ± 3.1

16.4 ± 2.6

> 0.05

Hb (g/dl)

12.5 ± 0.6a

11.9 ± 1.1a

11.8 ± 1.2a

7.9 ± 1.2b

< 0.05

Hematocrit (%)

37.6 ± 2.1a

35.8 ± 2.4a

35.5 ± 1.5a

23.6 ± 2.1b

< 0.05

MCV (fl)

92.3 ± 7.0a

87.8 ± 5.1a

86.8 ± 4.6a

61.1 ± 3.1b

< 0.05

MCHC (%)

34.1 ± 2.6a

34.0 ± 2.1a

33.9 ± 2.3a

26.1 ± 2.4b

< 0.05

Serum iron (ug/dl)

95.1 ± 4.6a

89.8 ± 2.5a

55.8 ± 2.5b

20.6 ± 1.1c

< 0.05

TIBC(mg/dl)

264 ± 15a

254 ± 34a

391 ± 24b

483 ± 21c

< 0.05

Tsat (%)

36.0 ± 1.1a

35.4 ± 0.6a

14.3 ± 0.9b

4.3 ± 0.6c

< 0.05

Transferrin (umol/L)

34 ± 2.3a

36 ± 2.5a

35 ± 3.4a

76.2 ± 13.6b

< 0.05

Ferritin (ng/ml)

69.2 ± 4.1a

16.0 ± 1.6b

10.5 ± 1.3c

5.3 ± 1.1d

< 0.05

ZnPP (ug/dl)

27 ± 1.3a

28 ± 2.3a

129 ± 10.1b

134 ± 12.3b

< 0.01

Urinary hepcidin-25 (nmol/mmol Cr)

2.8 ± 1.3a

0.7 ± 0.22b

0.3 ± 0.09c

.079 ± .009d

< 0.01

  1. The P value is for the difference between all groups by ANOVA test. aa, bb = non-significant (p > 0.05). ab, ac, ad = significant (P < 0.05). bc, bd, cd = significant (P < 0.05). *Chi-square test. Tsat = Transferrin saturation, ZnPP = erythrocyte zinc protoporphyrin.