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Table 2 List of studies analyzing the long-term prevalence of obesity in childhood after the end of ALL treatment.

From: Obesity in patients with acute lymphoblastic leukemia in childhood

Study Num.
Patients
Obesity definition Assessment period Obesity Prevalence (%)
Schell et al[63] 91 BMI > 24 kg/m2 Final height 38
Odame et al[6] 40 BMI > 97.7 th Diagnosis + 4 ys 57 (girls)
21 (boys)
Van Dongen-Melman[7] 113 BMI > 90 th Diagnosis + 4 ys 24
Didi et al[11] 114 BMI > 85 th Final height 46
Talvensaari et al[42] 50 Body weight > 120% ideal Diagnosis + 13 ys 32 (vs.10 in controls)
Birkebaech et al[34] 33 BMI > 90 th Final height 36
Nysom et al[30] 95 BMI > 90 th Diagnosis + 11 ys 25
Reilly et al[77] 98 BMI > 97.7 th Diagnosis + 3 ys 16
Shaw et al[65] 33 BMI > 85 th Final height 56 (girls)
13 (boys)
Sklar et al[28] 126 BMI ≥ 85th Final height Overall 30
18 Gy irradiated: 38
24 Gy irradiated: 40
Not irradiated: 30
Mayer et al[78] 39 (25 irradiated; 14CT only) NA 3.4-14.6 ys (from end of therapy) Overall 38
(48 irradiated, 21 CT only)
Meacham et al[64] 1665 BMI ≥ 30 kg/m2 Adulthood 18 (girls)
16.5 (boys)
Jarfelt et al[31] 35 BMI 25-29.9 kg/m2 20 ys (minimum: 15 ys) 34
Van Beck et al[50] 90 BMI ≥ 30 kg/m2 12.7 ys 8
Trimis et al[73] 80 NA 6.3 ys 25
Anser et al[79] 54 CT only BMI > 97.7 th Final Height 30 overweight
18 obese
Breene et al[40] 77 BMI SDS > 2.3 3 ys 47.2 (vs 29.9 at diagnosis)
  1. NA: Not Available; BMI: Body Mass Index; ys: years; CT: Chemotherapy.