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Table 2 List of studies analyzing the long-term prevalence of obesity in childhood after the end of ALL treatment.

From: Obesity in patients with acute lymphoblastic leukemia in childhood

Study

Num.

Patients

Obesity definition

Assessment period

Obesity Prevalence (%)

Schell et al[63]

91

BMI > 24 kg/m2

Final height

38

Odame et al[6]

40

BMI > 97.7 th

Diagnosis + 4 ys

57 (girls)

21 (boys)

Van Dongen-Melman[7]

113

BMI > 90 th

Diagnosis + 4 ys

24

Didi et al[11]

114

BMI > 85 th

Final height

46

Talvensaari et al[42]

50

Body weight > 120% ideal

Diagnosis + 13 ys

32 (vs.10 in controls)

Birkebaech et al[34]

33

BMI > 90 th

Final height

36

Nysom et al[30]

95

BMI > 90 th

Diagnosis + 11 ys

25

Reilly et al[77]

98

BMI > 97.7 th

Diagnosis + 3 ys

16

Shaw et al[65]

33

BMI > 85 th

Final height

56 (girls)

13 (boys)

Sklar et al[28]

126

BMI ≥ 85th

Final height

Overall 30

18 Gy irradiated: 38

24 Gy irradiated: 40

Not irradiated: 30

Mayer et al[78]

39 (25 irradiated; 14CT only)

NA

3.4-14.6 ys (from end of therapy)

Overall 38

(48 irradiated, 21 CT only)

Meacham et al[64]

1665

BMI ≥ 30 kg/m2

Adulthood

18 (girls)

16.5 (boys)

Jarfelt et al[31]

35

BMI 25-29.9 kg/m2

20 ys (minimum: 15 ys)

34

Van Beck et al[50]

90

BMI ≥ 30 kg/m2

12.7 ys

8

Trimis et al[73]

80

NA

6.3 ys

25

Anser et al[79]

54 CT only

BMI > 97.7 th

Final Height

30 overweight

18 obese

Breene et al[40]

77

BMI SDS > 2.3

3 ys

47.2 (vs 29.9 at diagnosis)

  1. NA: Not Available; BMI: Body Mass Index; ys: years; CT: Chemotherapy.