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Table 4 Ability of TSB measurements over the 50th, the 75th and the 90th percentile of TSB nomogram to predict significant hyperbilirubinaemia, for designated time periods.

From: Development and validation of serum bilirubin nomogram to predict the absence of risk for severe hyperbilirubinaemia before discharge: a prospective, multicenter study

Hours of age TP
(n)
FN
(n)
TN
(n)
FP
(n)
Sensitivity
(%)
Specificity
(%)
PPV
(%)
NPV
(%)
24 to 48 hours         
< 50 th percentile 24 1 357 263 96.0 57.6 8.4 99.7
< 75 th percentile 22 3 479 141 88.0 77.3 13.5 99.4
< 90 th percentile 12 13 576 44 48.0 92.9 21.4 97.8
49 to 72 hours         
< 50 th percentile 23 0 657 368 100 64.1 5.9 100
< 75 th percentile 22 1 860 165 95.7 83.9 11.8 99.9
< 90 th percentile 17 6 975 50 73.9 95.1 25.4 99.4
73 to 96 hours         
< 50 th percentile 7 0 322 145 100 69.0 4.6 100
< 75 th percentile 7 0 409 58 100 87.6 10.8 100
< 90 th percentile 6 1 446 21 85.7 95.5 22.2 99.8
  1. TP True Positive; FN False Negative; TN True negative; FP False Positive; PPV Positive Predictive Value; NPV Negative Predictive Value