Development and validation of serum bilirubin nomogram to predict the absence of risk for severe hyperbilirubinaemia before discharge: a prospective, multicenter study

Table 4 Ability of TSB measurements over the 50^th, the 75^th and the 90^th percentile of TSB nomogram to predict significant hyperbilirubinaemia, for designated time periods.

Hours of age	TP (n)	FN (n)	TN (n)	FP (n)	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
24 to 48 hours
< 50 ^th percentile	24	1	357	263	96.0	57.6	8.4	99.7
< 75 ^th percentile	22	3	479	141	88.0	77.3	13.5	99.4
< 90 ^th percentile	12	13	576	44	48.0	92.9	21.4	97.8
49 to 72 hours
< 50 ^th percentile	23	0	657	368	100	64.1	5.9	100
< 75 ^th percentile	22	1	860	165	95.7	83.9	11.8	99.9
< 90 ^th percentile	17	6	975	50	73.9	95.1	25.4	99.4
73 to 96 hours
< 50 ^th percentile	7	0	322	145	100	69.0	4.6	100
< 75 ^th percentile	7	0	409	58	100	87.6	10.8	100
< 90 ^th percentile	6	1	446	21	85.7	95.5	22.2	99.8

TP True Positive; FN False Negative; TN True negative; FP False Positive; PPV Positive Predictive Value; NPV Negative Predictive Value

ISSN: 1824-7288