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Table 3 Comparison between patients’ characteristics, consanguinity and family history rate of the three groups

From: The expanded clinical profile and the efficacy of colchicine therapy in Egyptian children suffering from familial mediterranean fever: a descriptive study

Item

Heterozygous (n=40)

Homozygous (n=20)

Gene-ve (n=10)

P-value

Age of onset (yeas), mean ± SD

5.20 ± 2.51

4.32 ± 2.58

4.63 ± 2.76

0.35

Age at diagnosis (years), mean ± SD

7.81 ± 2.79

6.01 ± 2.75

6.76 ± 3.08

0.07

Time interval between disease onset and diagnosis (years)

    

Mean ± SD

2.63 ± 1.63

1.75 ± 1.03

2.15 ± 1.94

0.13

Median (range)

2 (1–6)

1.8 (1–4)

1.3 (1–7)

 

Duration of follow-up (years), mean ± SD

2.18 ± 1.41

3.80 ± 3.24

2.95 ± 2.77

0.11

Median (range)

1.75 (1–6)

2 (1–11)

1.95 (1 – 9)

 

Male/Female

21/19

12/8

7/3

0.58

Consanguinity (n%)

14 (35%)

11 (55%)

1 (10%)

0.05

Family history of FMF (n%)

7 (17.5%)

7 (35%)

0 (0%)

0.06

Family history of amyloidosis (n%)

4 (10%)

0 (0%)

0 (0%)

0.20

  1. FMF= familial Mediterranean fever.
  2. *P-value less than 0.05 is considered statistically significant.