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Table 3 Sensitivity, Specificity, PPV, NPV of different parameters considered as predictors of malformations

From: Intrauterine growth restriction and congenital malformations: a retrospective epidemiological study

  Sensitivity 95%CI Specificity 95%CI PPV 95%CI NPV 95%CI p value
Smoke 13.21% 5.48- 25.34 88.00% 86.05 - 90.07 5.38% 2.19 - 10.78 95.22% 93.68 - 96.48 0.76
Pregnancy disease 24.53% 13.75-38.28 67.50% 64.56 - 70.34 3.70% 1.99 - 6.25 94.61% 92.73 - 96.12 0.23
SGA 13.21% 5.48 - 25.34 87.38% 85.20 - 89.34 5.07% 2.06 - 10.17 95.17% 93.61 - 96.44 0.97
Perc < 3 3.77% 0.46 - 12.98 96.24% 94.90 - 97.31 4.88% 0.60 - 16.53 95.14% 93.66 - 96.36 0.99
PI < 2.4 29.41% 17.49- 43.83 88.19% 86.06 - 90.10 10.95% 6.26 - 17.41 96.20% 94.76 - 97.32 0.00019
SGA & PI < 2.4 5.88% 1.23 - 16.24 95.15% 93.66 - 96.38 5.66% 1.18 - 15.66 95.33% 93.86 - 96.54 0.74
SGA OR PI < 2.4 35.29% 22.43- 49.93 80.31% 77.75 - 82.60 8.14% 4.90 - 12.57 96.17% 94.66 - 97.35 0.007
  1. PPV = Positive predictive value; NPV = Negative predictive value; CI = Confidence interval; Perc = weight percentile at birth; PI = Ponderal index at birth; SGA = Small for gestational age newborn.