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Table 3 Sensitivity, Specificity, PPV, NPV of different parameters considered as predictors of malformations

From: Intrauterine growth restriction and congenital malformations: a retrospective epidemiological study

 

Sensitivity

95%CI

Specificity

95%CI

PPV

95%CI

NPV

95%CI

p value

Smoke

13.21%

5.48- 25.34

88.00%

86.05 - 90.07

5.38%

2.19 - 10.78

95.22%

93.68 - 96.48

0.76

Pregnancy disease

24.53%

13.75-38.28

67.50%

64.56 - 70.34

3.70%

1.99 - 6.25

94.61%

92.73 - 96.12

0.23

SGA

13.21%

5.48 - 25.34

87.38%

85.20 - 89.34

5.07%

2.06 - 10.17

95.17%

93.61 - 96.44

0.97

Perc < 3

3.77%

0.46 - 12.98

96.24%

94.90 - 97.31

4.88%

0.60 - 16.53

95.14%

93.66 - 96.36

0.99

PI < 2.4

29.41%

17.49- 43.83

88.19%

86.06 - 90.10

10.95%

6.26 - 17.41

96.20%

94.76 - 97.32

0.00019

SGA & PI < 2.4

5.88%

1.23 - 16.24

95.15%

93.66 - 96.38

5.66%

1.18 - 15.66

95.33%

93.86 - 96.54

0.74

SGA OR PI < 2.4

35.29%

22.43- 49.93

80.31%

77.75 - 82.60

8.14%

4.90 - 12.57

96.17%

94.66 - 97.35

0.007

  1. PPV = Positive predictive value; NPV = Negative predictive value; CI = Confidence interval; Perc = weight percentile at birth; PI = Ponderal index at birth; SGA = Small for gestational age newborn.