From: Serum hepcidin: indication of its role as an “acute phase” marker in febrile children
Δvar = var1-var2 | Viral infection (n = 13) | Bacterial infection (n = 9) | P* |
---|---|---|---|
Age (months) | 22.8(±31.75), 8.5 (1 ~ 108) | 35.66(±45.79), 18 (2 ~ 144) | |
Male gender (%) | 7(53.85%) | 6(66.67%) | |
Hepcidin1 | 90.52(±50.97), 79.44(11.42 ~ 210.18) | 72.63(±39.95), 74.10(10.61 ~ 133.8) | 0.48 |
Hepcidin2 | 53.18(±22.46), 46.17(27.12 ~ 100.73) | 42.34(±28.83), 33.14(18.39 ~ 115.73) | 0.12 |
Δhepcidin(1 → 2) | 37.34(±59.89), 33.48(-89 ~ 178.74) | 30.28(±38.25), 34.99(-39.44 ~ 87.61) | 0.86 |
P** | 0.033 | 0.05 | |
Ferritin1 | 135.98(±106.36), 68.12(30.1 ~ 333.3) | 160.01(±117.97), 106.5(73.57 ~ 457.3) | 0.24 |
Ferritin2 | 50.66(±37.55), 34.5(14 ~ 160) | 67.65(±54.01), 39.3(12.4 ~ 173) | 0.5 |
Δferritin(1 → 2) | 85.31(±106.86), 35.58(-25.9 ~ 292.58) | 92.36(±142.80), 51.7(-69 ~ 421.95) | 0.71 |
P** | 0.0046 | 0.05 | |
Serum iron1 | 29.69(±17.07), 28(9 ~ 69) | 15.66(±4.58), 16(10 ~ 25) | 0.015 |
Serum iron 2 | 47.69(±20.34), 46(21 ~ 76) | 46.33(±27.83), 42(18 ~ 115) | 0.61 |
ΔSerum iron (1 → 2) | -18(±29.76), -17(-67 ~ 48) | -30.66(±28.35), -24(-98 ~ 7) | 0.24 |
P** | 0.039 | 0.01 | |
Hb1(gr/dl) | 11.74(±1.91), 11.7(8.1 ~ 15.5) | 11.4(±1.24), 11(10.2 ~ 13.7) | 0.59 |
Hb2 (gr/dl) | 11.93(±0.92), 11.8(10.6 ~ 13.7) | 12.66(±0.87), 12.1(11.7 ~ 13.9) | 0.065 |
ΔHb(1 → 2) | -0.19(±1.63), -0.69(-2.5 ~ 3.7) | -1.26(±0.95), -1.1(-3.4 ~ -0.19) | 0.17 |
P** | 0.46 | 0.007 | |
Hct1 (%) | 35.82(±5.62), 35.8(24.6 ~ 45.9) | 34.5(±3.74), 32.9(30.3 ~ 41) | 0.48 |
Hct2 (%) | 35.30(±2.71), 35(32 ~ 40.5) | 38.53(±2.48), 38.7(35.6 ~ 42) | 0.01 |
Δhct(1 → 2) | 0.51(±4.65), -0.70(-7.9 ~ 10.7) | -4.03(±3.02), -3.1(-10.4 ~ -1) | 0.01 |
P** | 0.86 | 0.007 | |
MCHC1 | 29.84(±1.58), 30(26 ~ 32.8) | 29.36(±1.33), 29(27.5 ~ 31.3) | 0.29 |
MCHC2 | 30.23(±1.20), 30(28 ~ 32) | 30.36(±1.13), 30.2(28 ~ 32.1) | 0.68 |
Δmchc(1 → 2) | -0.38(±1.41), -0.5(-3 ~ 2) | -1.0(±1.15), -1(-3 ~ 0.5) | 0.34 |
P** | 0.32 | 0.028 | |
reticulocytes1(%) | 1.21(±0.66), 1(0.5 ~ 2.7) | 1.6(±0.64), 1.5(0.6 ~ 2.4) | 0.16 |
reticulocytes 2 (%) | 0.86(±0.35), 0.8(0.3 ~ 1.4) | 0.8(±0.36), 0.7(0.3 ~ 1.6) | 0.66 |
Δreticulocytes (1 → 2) | 0.35(±0.74), 0.3(-0.8 ~ 2.1) | 0.8(±0.64), 0.6(0–1.7) | 0.13 |
P** | 0.10 | 0.012 | |
ESR1 (mm/1 h) | 17.38(±8.11), 15(5 ~ 31) | 37.66(±14.04), 38(19 ~ 70) | 0.0007 |
ESR2 (mm/1 h) | 11.38(±8.7), 9(4 ~ 35) | 12.44(±8.5), 10(4 ~ 30) | 0.68 |
ΔESR(1 → 2) | 6.0(±12.32), 3(-15 ~ 26) | 25.22(±12.36), 26(8 ~ 49) | 0.0033 |
P** | 0.1 | 0.007 | |
WBC1/mm3 | 10205(±3806), 10100(4200 ~ 18200) | 23133(±13813), 17400(9300 ~ 50100) | 0.005 |
WBC2/mm3 | 10100(±3003), 8900(6000 ~ 16800) | 10855(±5008), 10400(4700 ~ 21100) | 0.86 |
Δwbc(1 → 2) | 115(±4306), 200(-6300 ~ 9700) | 12277(±12920), 7700(-4000 ~ 34100) | 0.016 |
P** | 0.94 | 0.02 | |
N1 (%) | 47.38(±24.59), 54(11 ~ 89) | 69.55(±16.43), 66(40 ~ 89) | 0.02 |
N2 (%) | 37.07(±11.62), 35(21 ~ 63) | 37.17(±15.87), 41(10 ~ 55) | 0.73 |
ΔN(1 → 2) | 10.3(±18.19), 16(-24 ~ 33) | 37.37(±18.42), 37(-1 ~ 56) | 0.01 |
P** | 0.063 | 0.0109 | |
L1 (%) | 37.3(±23.08), 33(5 ~ 72) | 19.88(±10.44), 23(6 ~ 33) | 0.08 |
L2 (%) | 49.61(±14.20), 52(27 ~ 72) | 48.63(±18.18), 45(32 ~ 82.5) | 0.78 |
ΔL(1 → 2) | -12.3(±18.71), -17(-39 ~ 24) | -28.74(±16.85), -28(-55.5 ~ -7) | 0.065 |
P** | 0.042 | 0.007 | |
M1 (%) | 12.38(±5.79), 12(6 ~ 24) | 8.66(±5.52), 6(3 ~ 20) | 0.069 |
M2 (%) | 8.23(±2.80), 7(4 ~ 13) | 10.03(±3.45), 10(6 ~ 16) | 0.19 |
ΔM(1 → 2) | 4.15(±6.4), 2(-4 ~ 18) | -1.36(±6.39), -3(-10 ~ 10) | 0.034 |
P** | 0.072 | 0.4 | |
CRP1 (mg/dl) | 17.07(±24.69), 12(0 ~ 93) | 100.88(±59.50), 92(24 ~ 178) | 0.0006 |
CRP2 (mg/dl) | 4.57(±5.48), 1(0 ~ 17) | 5.11(±9.51), 2(0 ~ 30) | 0.91 |
Δcrp(1 → 2) | 12.5(±23.08), 7(-9 ~ 82) | 95.77(±64.87), 90.5(-6 ~ 173) | 0.0037 |
P** | 0.022 | 0.0109 | |
PLT1 /mm3 | 382923(±162607), 335000(191000 ~ 758000) | 465444(±162687), 438000(215000 ~ 709000) | 0.19 |
PLT2 /mm3 | 275538(±63602), 278000(198000 ~ 403000) | 302555(±48844), 303000(230000 ~ 383000) | 0.25 |
ΔPLT(1 → 2) | 107384(±137673), 44000(-84000 ~ 355000) | 162888(±132197), 120000(-41000 ~ 326000) | 0.3 |
P** | 0.015 | 0.0109 |