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Table 1 Criteria of positivity for oral food challenge according to Powell [[6]]

From: Food protein induced enterocolitis syndrome caused by rice beverage

Preparatory steps

Observe/test for criteria*

Emergency therapies in place (i.e. intravenous access)

Vomiting, diarrhoea

Verify normal weight gain and lack of symptoms while avoiding potential causal protein

Faecal blood (frank or occult)

Baseline and follow-up stool samples

Faecal leucocytes

Baseline peripheral blood PNM count

Faecal eosinophils

Repeat peripheral blood PNM count 6 h after ingestion

Increase of neutrophils >3.500/mm3

  1. *Oral food challenge is considered positive when three or more criteria are satisfied.