|
O’Sullivan et al. [17]
|
66
|
DPNB (ultrasound or anatomical landmark) / fentanyl
|
ukn*
|
FLACC
|
No significant difference between the groups in terms of fentanyl administration. The ultrasound technique took longer to perform but suggests some benefits in terms of postoperative pain.
|
2011
|
|
Banieghbal et al. [18]
|
583
|
RB/milk
|
Gomco
|
NIPS
|
RB causes a painful response in the majority of the babies, but this is mostly noted in babies over one week of age.
|
2009
|
|
Lehr et al. [19]
|
44
|
DPNB/EMLA/lidocaine
|
Gomco
|
NFCS/crying time
|
No significant difference in analgesic efficacy between treatments.
|
2007
|
|
Garry et al. [20]
|
18
|
DPNB/EMLA
|
ukn*
|
NIPS/numeric pain scale
|
DPNB is significantly more effective for pain relief than topical EMLA.
|
2006
|
|
Lehr et al. [21]
|
53
|
DPNB/EMLA/lidocaine
|
Gomco
|
Heart rate/respiratory rate/SpO2
|
No significant difference in analgesic efficacy between treatments.
|
2005
|
|
South et al. [22]
|
44
|
DPNB/Tylenol/non-nutritive sucking
|
Gomco
|
PIPP/crying time/ salivary cortisol level
|
NNS significantly decreases the pain response, in addition to other common analgesics.
|
2005
|
|
Razmus et al. [23]
|
132
|
DPNB/DPNB+sucrose/ DPNB+sucrose+EMLA/ EMLA/ EMLA+sucrose/ RB/ RB+sucrose solution/ sucrose solution
|
ukn*
|
FLACC
|
DPNB and RB in combination with the concentrated oral sucrose have the lowest pain scores. The sucrose alone does not provide sufficient analgesia; however, it can reduce the pain scores somewhat when used in conjunction with other analgesics.
|
2004
|
|
Malnory et al. [24]
|
53
|
Acetaminophen
|
Gomco
|
NIPS
|
Lower pain scores in newborns who received analgesia than placebo.
|
2003
|
|
Taeusch et al. [25]
|
59
|
DPNB/dextrose solution
|
Mogen vs PlastiBell
|
Cry response
|
The Mogen technique is preferred over the PlastiBell because of the simplicity of execution, and it is also associated with less pain and discomfort and it takes less time.
|
2002
|
|
Kaufman et al. [26]
|
57
|
EMLA/sucrose solution
|
Mogen vs Gomco
|
Crying time/ facial grimancing
|
Mogen appears a better procedure than Gomco, and it takes less time, showing also that the use of analgesia is imperative.
|
2002
|
|
Macke et al. [27]
|
60
|
Acetaminophen
|
Gomco
|
NCAFS/crying time/heart rate
|
No significant difference in analgesic efficacy between treatments and placebo.
|
2001
|
|
Joyce et al. [28]
|
23
|
EMLA/music
|
ukn*
|
RIPS/heart rate/SpO2/salivary cortisol level/crying time
|
Efficacy of EMLA and music to contribute to the pain relief of neonates undergoing circumcision.
|
2001
|
|
Kass et al. [29]
|
71
|
DPNB/dextrose solution
|
Gomco
|
MBPS/ crying time/heart rate/respiratory rate
|
No significant differences between the oral glucose and water groups among any of the pain-related measurements; only the use of DPNB shows significantly lower pain scores and reduced objective measurements of pain and physiologic stress.
|
2001
|
|
Taddio et al. [30]
|
86
|
DPNB/EMLA/acetaminophen
|
Mogen vs Gomco
|
NFCS/crying time
|
Infants circumcised with the Mogen clamp and combined analgesia have also less pain than those circumcised with the Gomco clamp and EMLA cream, and it also takes less time.
|
2000
|
