The prevalence and risk factors of allergic and respiratory symptoms in a regional cohort of extremely low birth weight children (<1000 g)

Table 2 Laboratory tests results in the studied groups

	ELBW group	Control group	p value
	N=22	N=20
Spirometry and bronchial responsiveness (expressed as mean ± SD)
FEV₁ (%)	81.3±13	95.8±8	<0.001^a
FVC (%)	79±13	89±7	<0.001^a
MEF₅₀ (%)	62±19	87±26	<0.001^a
Δ%FEV₁ (%)	6.8±12.3	3.6±5.9	0.3^a
Δ%MEF₅₀ (%)	31±32	19±17	0.15^a
FEV₁ < 80% predicted value	10 (45%)	0	0.001^b
Δ%FEV₁ >12%	4 (18%)	1 (5%)	0.3^b
FeNO (ppb)
Median (25^th-75^th percentile)	8 (8–13)	10 (8–14)	0.2^c
Normal (≤20 ppb)	22	15	0.02^b
Intermediate (20–35 ppb)	0	3
High (>35 ppb)	0	2
	N=81	N=40
serum tIgE (kU/L)
Geometric mean (± SD)	32±4	56±4	0.002^a
High (>upper limit for age)	10 (12%)	12 (32%)	0.02^b
Others
Absolute eosinophil count per uL)	265±202	225±185	0.3^a
Positive SPT	8 (11%)	9 (24%)	0.09^b

ISSN: 1824-7288