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Table 1 Pediatric rhinocerebral zygomycosis: review of the literature from 1980 to 2013

From: Rhinocerebral zygomycosis with pansinusitis in a 14-year-old girl with type 1 diabetes: a case report and review of the literature

Author Cases (Number) Sex Ages (years) Underlying condition Treatment Outcome
Kilpatrick et al. [4]. 1984 1 F 18 DM 1 Surgery, antifungal therapy Survived with left orbital exenteration and ethmoidectomy.
Kemper et al. [5]. 1993 1 F 18 DM 1 Surgery, L-AmB, HOT Survived with right eye exenteration
Garces et al. [6]. 1994 1 M 6 Hematologic malignancy Surgery Deceased
Moll et al. [7]. 1994 1 Unknown 12 DM 1 Surgery, antifungal therapy Survived with minimal left cranial nerve palsies
Shah et al. [8]. 1997 1 M 15 DM 1 L-AmB and HOT Survived with a ventriculoperitoneal shunt, right nonreactive pupil, minimal residual physical disability
Kameh et al. [9] 1997 1 M 13 months DM 1 Surgery, L-AmB Deceased
Adler et al. [10]. 1998 1 M 16 DM 1 Surgery, L-AmB Survived
Lee et al. [11] 1998 1 M 10 DM 1 Surgery, L-AmB Survived with open craniotomy for abscess resection
Khanna et al. [12]. 1998 1 F 11 DM 1 Surgery, L-AmB Deceased
Parkin et al. [13]. 2000 2 M; M 13; 3 Hematologic malignancy G-CSF, L-AmB Deceased for other cause; survived after bone marrow transplant
Ryan et al. [14]. 2001 2 F; M 9;3 Hematologic malignancy Surgery, L-AmB Deceased
Gessesse et al. [15]. 2001 1 M 11 DM 1 Unknown Deceased
Wehl et al. [16]. 2002 1 M 9 months Hematologic malignancy L-AmB Deceased
Hamilton et al. [17]. 2003 1 M 14 DM 1 Surgery, antibiotics, HOT Survived with enucleation of right eye
Simmons et al. [18]. 2005 1 F 8 DM 1 Surgery, L-AmB, HOT, Interferon-G, POS, GM-CSF Survived
Sorensen et al. [19]. 2006 1 F 10 Hematologic malignancy L-AmB, POS, Caspofungin, surgery Deceased for other cause
Popa et al. [20] 2008 1 F 7 Hematologic malignancy L-AmB Survived after neurosurgical debridement of the left temporal abscess
Garner et al. [21]. 2008 2 M; M 5; 15 Hematologic malignancy L-AmB, POS Survived
Ganesh et al. [22] 2008 1 M 14 DM 1 L-AmB, itraconazole Survived
Tarani et al. [23]. 2009 1 F 12 DM 1 L-AmB, GM-CSF, HOT, surgery, POS Survived
Ibrahim et al. [24]. 2009 1 F 12 DM 1 L-AmB, POS Survived
Skiada et al. [3]. 2009 1 M 2 Hematologic malignancy L-Am B, POS Vegetative state
Safder et al. [25]. 2010 1 F 12 Autoimmune hepatitis Surgery, L-AmB Survived with right eye exenteration
Nirmala et al. [26]. 2011 1 M 12 DM 1 L-AmB Survived
Prasad et al. [27]. 2012 1 F 15 Hematologic malignancy Surgery and L-AmB Deceased
  1. Abbreviations: M Male, F Female, DM 1 Type 1 Diabetes, L-Amb Liposomal Amphotericin B, HOT Hyperbaric Oxygen Therapy, POS Posaconazole, GM-CFS Granulocyte Macrophage Colony Stimulating Factor.