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Table 4 Ability of TcB measurements over the 50th, the 75th and the 90th percentile of TcB nomogram to predict significant hyperbilirubinaemia, for designated time periods

From: Italian guidelines for management and treatment of hyperbilirubinaemia of newborn infants ≥ 35 weeks’ gestational age

Hours of life

TP

FN

TN

FP

Sensitivity

Specificity

PPV

NPV

24 - 48 hours

        

<50th percent

27

0

161

460

100%

25.9%

5.5%

100%

<75th percent

25

2

429

192

92.6%

69.1%

11.5%

99.5%

<90th percent

14

13

564

57

51.9%

90.8%

19.7%

97.7%

49 - 72 hours

        

<50th percent

21

0

410

615

100%

40%

3.3%

100%

<75th percent

21

0

702

323

100%

68.5%

6.1%

100%

<90th percent

18

3

888

137

85.7%

86.6

11.6%

99.7%

73 - 96 hours

        

<50th percent

7

0

246

220

100%

52.8%

3.1%

100%

<75th percent

7

0

348

118

100%

74.7%

5.6%

100%

<90th percent

5

2

409

57

71.4%

87.8%

8.1%

99.5%