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Table 5 Ability of TSB measurements over the 50th, the 75th and the 90th percentile of TSB nomogram to predict significant hyperbilirubinaemia, for designated time periods

From: Italian guidelines for management and treatment of hyperbilirubinaemia of newborn infants ≥ 35 weeks’ gestational age

Hours of life

TP

FN

TN

FP

Sensitivity

Specificity

PPV

NPV

24 - 48 hours

        

<50th percent

24

1

357

263

96.0%

57.6%

8.4%

99.7%

<75th percent

22

3

479

141

88.0%

77.3%

13.5%

99.4%

<90th percent

12

13

576

44

48.0%

92.9%

21.4%

97.8%

49 - 72 hours

        

<50th percent

23

0

657

368

100%

64.1%

5.9%

100%

<75th percent

22

1

860

165

95.7%

83.9%

11.8%

99.9%

<90th percent

17

6

975

50

73.9%

95.1%

25.4%

99.4%

73 - 96 hours

        

<50th percent

7

0

322

145

100%

69.0%

4.6%

100%

<75th percent

7

0

409

58

100%

87.6%

10.8%

100%

<90th percent

6

1

446

21

85.7%

95.5%

22.2%

99.8%