Table 1 Characteristics and genotype distributions in asthmatics and controlsª
Asthmatics | Controls | P-value | OR | 95% CI | |
|---|---|---|---|---|---|
Age (Mean ± SD), years | 7.65 ± 1.916 | 8.27 ± 1.785 | 0.025* | _ | _ |
Sex | _ | _ | |||
Male | 62 (66%) | 44 (48.9%) | 0.019* | ||
Female | 32 (34%) | 46 (51.1%) | |||
Spirometry | _ | _ | _ | ||
FEV1 (%predicted)** | 97 ± 6.2 | _ | |||
FVC (%predicted)*** | 96 ± 8.2 | ||||
Disease severity | |||||
Mild persistent | 21 (22%) | _ | _ | _ | _ |
Moderate persistent | 36 (38.3%) | ||||
Severe persistent | 37 (39.3%) | ||||
Atopy | |||||
Atopic | 67 (71.3%) | _ | _ | _ | |
Non atopic | 27 (28.7%) | 90 (100%) | |||
Passive smoking exposure | 39 (41.5%) | 28 (31.1%) | 0.168 | _ | _ |
GSTT1 | |||||
Null | 82 (87.2% | 88 (97.8%) | |||
Present | 12 (12.8%) | 2 (2.2%) | 0.007* | 0.683 | 0.034-0.715 |
GSTM1 | |||||
Null | 47 (50%) | 55 (61.1%) | |||
Present | 47 (50%) | 35 (38.9%) | 0.130 | 1.000 | 0.539-1.857 |