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Table 3 Echocardiographic parameters measured before the administration of surfactant (T0), and 2 hours (T1) and 24 hours (T2) after

From: Pilot observational study on haemodynamic changes after surfactant administration in preterm newborns with respiratory distress syndrome

  T0 T1 T2 p value p value p value
T0 vs T1 T0 vs T2 T1 vs T2
AT/RVET 0.25 ± 0.05 0.30 ± 0.06 0.33 ± 0.06 0.066 0.001 0.011
Left ventricle       
E (cm/sec) 40.84 ± 11.84 40.24 ± 4.63 45.85 ± 15.56 0.953 0.272 0.374
A (cm/sec) 51.13 ± 14.98 49.47 ± 7.79 52.12 ± 14.2 0.260 0.925 0.260
E/A 0.81 ± 0.13 0.83 ± 0.13 0.88 ± 0.17 0.192 0.300 0.314
LVO (ml/Kg/min) 204.13 ± 65.24 210.89 ± 76.42 227.91 ± 77.41 0.779 0.041 0.327
RVO (ml/Kg/min) 220.82 ± 95.57 265.08 ± 65.88 256.86 ± 113.09 0.674 0.050 0.889
Left ventricle       
 S’ 3.26 ± 0.51 3.50 ± 0.64 3.52 ± 0.67 0.085 0.372 0.953
 E’ 4.75 ± 1.01 4.59 ± 0.77 5.02 ± 1.54 0.406 0.593 0.086
 A’ 4.16 ± 1.13 4.56 ± 1.57 5.05 ± 2.04 0.314 0.124 0.260
Right ventricle       
 S’ 4.64 ± 0.75 4.60 ± 1.05 5.27 ± 0.87 0.859 0.035 0.260
 E’ 5.47 ± 1.12 5.67 ± 1.12 6.24 ± 1.69 0.214 0.198 0.515
 A’ 6.88 ± 1.37 7.08 ± 1.78 7.48 ± 0.97 0.678 0.272 0.374
Left ventricle       
 E/E’ 8.77 ± 2.46 8.98 ± 1.60 9.48 ± 3.06 0.953 0.509 0.767
TAPSE (cm) 0.72 ± 0.17 0.73 ± 0.12 0.85 ± 0.13 0.767 0.002 0.008
  1. Data are presented as mean ± SD. Significant p values are reported in bold.
  2. AT: acceleration time; RVET: right ventricular ejection time; LVO: left ventricular output; RVO: right ventricular output; TAPSE: Tricuspidal Annular Plane Systolic Excursion.