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Table 2 Genotypes and allele frequencies of the polymorphisms of the NOS genes in RDS and control groups and their association with the risk of RDS

From: Analysis of nitric oxide synthase gene polymorphisms in neonatal respiratory distress syndrome among the Chinese Han population

Genotypes/Alleles Control group (n = 227) n (%) RDS group (n = 189) n (%) P value OR (95% CI)
rs2682826 (NOS1)     
  GG 99 (43.6) 86 (45.5)   
  GA 107 (47.1) 75 (39.7) 0.308 0.807 (0.534–1.200)
  AA 21 (9.3) 28 (14.8) 0.201 1.535 (0.813–2.897)
  G allele 305 (67.2) 247 (65.3)   
  A allele 149 (32.8) 131 (34.7) 0.577 1.086 (0.814–1.449)
rs1799983 (NOS3)     
  GG 134 (59.0) 127 (67.2)   
  GT 88 (38.8) 57 (30.2) 0.070 0.683 (0.453–1.032)
  TT 5 (2.2) 5 (2.6) 1.000 1.055 (0.298–3.731)
  G allele 356 (78.4) 311 (82.3)   
  T allele 98 (21.6) 67 (17.7) 0.164 0.783 (0.554–1.106)