Genotype/Allele | Control group (n = 227) | RDS group (n = 189) | P value | OR (95% CI) |
---|---|---|---|---|
Gestational age | ||||
26w ≤ GA < 33 W | n = 80 | n = 117 | ||
GG | 33 (41.3) | 77 (65.8) | ||
GT | 45 (56.3) | 36 (30.8) | 0.001 | 0.343 (0.188-0.624) |
TT | 2 (2.4) | 4 (3.4) | 1.000 | 0.857 (0.150-4.911) |
G allele | 111 (69.4) | 190 (81.2) | ||
T allele | 49 (30.6) | 44 (18.8) | 0.007 | 0.525 (0.328-0.839) |
33w ≤ GA < 37 W | n = 147 | n = 72 | ||
GG | 101 (68.7) | 50 (69.4) | ||
GT | 43 (29.3) | 21 (29.2) | 1.000 | 0.987 (0.530-1.838) |
TT | 3 (2.0) | 1 (1.4) | 1.000 | 0.673 (0.068-6.639) |
G allele | 245 (83.3) | 121 (84.0) | ||
T allele | 49 (16.7) | 23 (16.0) | 0.892 | 0.950 (0.553-1.633) |
Birth weight | ||||
BW < 1.5 | n = 21 | n = 64 | ||
GG | 10 (47.6) | 44 (68.8) | ||
GT | 11 (52.4) | 15 (23.4) | 0.031 | 0.310 (0.110-0.875) |
TT | 0 (0) | 5 (7.8) | - | - |
G allele | 31 (73.8) | 103 (80.5) | ||
T allele | 11 (26.2) | 25 (19.5) | 0.387 | 0.684 (0.303-1.545) |
1.5 < BW < 2.5 | n = 105 | n = 106 | ||
GG | 73 (69.5) | 71 (67.0) | ||
GT | 30 (28.6) | 35 (33.0) | 0.554 | 1.200 (0.667-2.157) |
TT | 2 (1.9) | 0 (0) | - | - |
G allele | 176 (83.8) | 177 (83.5) | ||
T allele | 34 (16.2) | 35 (16.5) | 1.000 | 1.024 (0.611-1.715) |
BW > 2.5 | n = 101 | n = 19 | ||
GG | 51 (50.5) | 12 (63.2) | ||
GT | 47 (46.5) | 7 (36.8) | 0.455 | 0.633 (0.230-1.743) |
TT | 3 (3.0) | 0 (0) | - | - |
G allele | 149 (73.8) | 31 (81.6) | ||
T allele | 53 (26.2) | 7 (18.4) | 0.414 | 0.635 (0.264-1.527) |