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Table 5 Effect of rs1799983 polymorphism of NOS3 gene on characteristics and severity of illness among RDS infants

From: Analysis of nitric oxide synthase gene polymorphisms in neonatal respiratory distress syndrome among the Chinese Han population

  GG genotype(n = 129 ) GT + TT genotype(n = 60 ) P value
Gestational age (weeks) 33.0 ± 2.5 31.3 ± 2.1 0.000
Birth weight (g) 2050 ± 575 1753 ± 373 0.000
Gender (male/female) 79/50 39/21 0.619
Mode of delivery (V/CS) 47/82 29/31 0.120
PROM > 18 h 41/88 22/38 0.507
Use of antenatal steroid 24/105 20/40 0.026
Use of surfactant 98/31 49/11 0.380
Days of oxygen 38.3 ± 23.4 39.8 ± 25.7 0.135
Days of ventilation 20.1 ± 13.4 19.7 ± 15.6 0.407
Days of hospitalization 43.8 ± 21.6 42.2 ± 17.3 0.075
Complications    
 PDA 27/102 18/42 0.173
 BPD 32/97 11/49 0.323
 ROP 11/118 9/51 0.178
 IVH 14/115 2/58 0.098
  1. V: Vaginal delivery; CS: cesarean section; PROM: premature rupture of membranes; PDA: patent ductus arteriosus; BPD: bronchopulmonary dysplasia; ROP: retinopathy of prematurity; IVH: intraventricular hemorrhage.