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Table 5 Effect of rs1799983 polymorphism of NOS3 gene on characteristics and severity of illness among RDS infants

From: Analysis of nitric oxide synthase gene polymorphisms in neonatal respiratory distress syndrome among the Chinese Han population

 

GG genotype(n = 129 )

GT + TT genotype(n = 60 )

P value

Gestational age (weeks)

33.0 ± 2.5

31.3 ± 2.1

0.000

Birth weight (g)

2050 ± 575

1753 ± 373

0.000

Gender (male/female)

79/50

39/21

0.619

Mode of delivery (V/CS)

47/82

29/31

0.120

PROM > 18 h

41/88

22/38

0.507

Use of antenatal steroid

24/105

20/40

0.026

Use of surfactant

98/31

49/11

0.380

Days of oxygen

38.3 ± 23.4

39.8 ± 25.7

0.135

Days of ventilation

20.1 ± 13.4

19.7 ± 15.6

0.407

Days of hospitalization

43.8 ± 21.6

42.2 ± 17.3

0.075

Complications

   

 PDA

27/102

18/42

0.173

 BPD

32/97

11/49

0.323

 ROP

11/118

9/51

0.178

 IVH

14/115

2/58

0.098

  1. V: Vaginal delivery; CS: cesarean section; PROM: premature rupture of membranes; PDA: patent ductus arteriosus; BPD: bronchopulmonary dysplasia; ROP: retinopathy of prematurity; IVH: intraventricular hemorrhage.
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Italian Journal of Pediatrics

ISSN: 1824-7288

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