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Table 1 Anthropometric measurements and lipid profile in the study population

From: Plant sterols–enriched diet decreases small, dense LDL-cholesterol levels in children with hypercholesterolemia: a prospective study

 

Hypercholesterolemic group

P

Controls baseline

P*

P**

Before plant sterols*

After plant sterols**

BMI

16.93 ± 2.64 16.65(13.1-21.6)

17.7 ± 2.89 17.1(13.2 ~ 22.4)

 

19.29 ± 3.08 18.8(13.1-27.8)

  

BMI- SDS

0.29 ± 1.31 0.27(−1.79-2.51)

0.48 ± 1.34 0.68(−1.91 ~ 2.2)

0.62

0.77 ± 1.28 0.9(−2.2 ~ 3.85)

0.55

0.68

sdLDL-C

1.06 ± 0.23 1.04(0.71-1.59)

0.92 ± 0.25 0.84(0.44-1.47)

<0.001

0.60 ± 0.11 0.64(0.33-0.78)

<0.001

<0.001

TC

7.00 ± 1.45 6.90(5.13-11.42)

6.34 ± 1.57 5.92(3.83-9.95)

<0.001

4.50 ± 0.54 4.60(3.26-5.56)

<0.001

<0.001

LDL-C

5.20 ± 1.37 4.91(3.50-9.27)

4.55 ± 1.57 4.27(2.20-8.31)

<0.001

2.59 ± 0.36 2.64(1.76-3.34)

<0.001

<0.001

NonHDL-C

5.49 ± 1.50 5.40(3.39-10.13)

4.81 ± 1.66 4.37(2.49-8.96)

<0.001

2.87 ± 0.44 3.03(1.94-3.57)

<0.001

<0.001

HDL-C

1.53 ± 0.44 1.53(0.57-2.72)

1.53 ± 0.41 1.53(0.91-2.85)

0.58

1.66 ± 0.47 1.58(0.98-2.64)

0.38

0.31

TGs

0.73 ± 0.33 0.64(0.36-1.63)

0.65 ± 0.24 0.60(0.35-1.40)

0.28

0.68 ± 0.25 0.63(0.28-1.24)

0.68

0.74

ApoA-I

50.88 ± 9.60 51.25 (31.67-86.87)

54.45 ± 12.46 53.02 (40.21-80.43)

0.22

53.02 ± 10.32 53.02 (32.74-77.94)

0.48

0.82

ApoB

2.38 ± 0.58 2.33(1.65-4.20)

2.09 ± 0.53 1.98(1.27-3.60)

0.004

1.31 ± 0.24 1.41(0.76-1.67)

<0.001

<0.001

Lp(a)§

1.04 ± 0.91 0.77(0.08-3.11)

1.2 ± 0.72 0.97 (0.09-2.68)

0.91

0.60 ± 0.68 0.31(0.08-2.08)

0.03

0.002

  1. Laboratory data are expressed as mean ± SD, median and range in mmol/l and in §μmol/l.
  2. Abbreviations: BMI: body mass index; BMI-SDS: body mass index standard deviation scores; sdLDL: small dense low density lipoprotein-cholesterol; TC: total cholesterol; LDL-C: low density lipoprotein-cholesterol; NonHDL-C: non high density lipoprotein-cholesterol; HDL-C: high density lipoprotein-cholesterol; TGs: triglycerides; ApoA-I: apolipoprotein A-I; ApoB: apolipoprotein B; Lp(a): lipoprotein (a).
  3. *comparison between hypercholesterolemic group before plant sterols and controls baseline **comparison between hypercholesterolemic group after plant sterols and controls baseline.