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Table 1 Main clinical features of 184 children affected by AD after a mean 10-year follow-up

From: Atopic dermatitis phenotypes in childhood

 

Non-IgE AD

IgE AD

IgE AD with respiratory diseases

IgE AD without respiratory diseases

Total

Patients N (%)

15 (8%)

169 (92%)

131 (78%)

38 (22%)

184

M (%)

7 (47%)

95 (56%)

74 (56%)

21 (55%)

102 (55%)

Family history of atopy N (%)

10 (67%)

120 (71%)

94 (72%)

26 (68%)

130 (71%)

Family history of AD N (%)

1 (7%)

23 (14%)

19 (15%)

4 (11%)

24 (13%)

Mean age at AD onset (months)

30 *

8 *

8

7

10

Mean age of AD remission (months)

119 **

61 **

65 $

36 $

66

Past or present food allergy/OAS

/

125 (74%)

94 (72%)

31 (82%)

125 (68%)

Mean age at food allergy/OAS onset (months)

/

16

18

9

 

Mean age at food allergy/OAS remission (months)

/

49

55 $$

37 $$

 

Wheezing

/

53 (31%)

53 (40%)

/

53 (29%)

Asthma

/

62 (37%)

62 (47%)

/

62 (34%)

Allergic Rhinitis N (%)

/

112 (66%)

112 (85%)

/

112 (61%)

  1. *P value = 0.0001; **P value = 0.0003; $P value = 0.0146; $$ P value = 0.035.
  2. IgE-associated AD (169 children) was divided in 2 subgroups: 1) with allergic respiratory symptoms (131 children); 2) without allergic respiratory symptoms (38 children). OAS = oral allergy syndrome.