Atopic dermatitis phenotypes in childhood

Table 2 Geometric mean (GM) of total (UI/mL) and specific (kU/L) IgE, and percentage of positivity in children with IgE-associated AD phenotype at different ages

IgE-mediated AD with respiratory diseases
Months	0-12		13-24		24-36		36-48		48-60		61-72		73-84
	(N = 25)		(N = 51)		(N = 49)		(N = 45)		(N = 53)		(N = 59)		(N = 47)
IgE (UI/mL)	64		128		232		260		306		367		549
sIgE (kU/L)	GM	%	GM	%	GM	%	GM	%	GM	%	GM	%	GM	%
Cow’s milk	6.2	48	3.0	63	2.4	69	1.6	53	2.0	42	2.0	37	2.1	38
Hen’s egg (white)	7.3	76	5.8	76	4.8	73	3.5	67	2.6	57	1.7	42	2.4	40
Phleum p.	0.8	12	1.4	14	2.0	47	4.7	69	8.3	72	13.5	63	16.9	87
Cynodon d.	0	2.3	6	1.6	38	3.0	51	3.7	60	7.2	49	9.4	81
D. pteronyssinus	1.1	12	1.5	10	4.0	18	5.5	40	8.0	40	9.1	39	11.0	53
D. farinae	0.5	8	1.1	10	2.6	22	6.9	40	8.5	34	7.3	37	13.7	49
IgE-mediated AD without respiratory diseases
Months	0-12		13-24		24-36		36-48		48-60		61-72		73-84
	(N = 13)		(N = 25)		(N = 25)		(N = 16)		(N = 15)		(N = 11)		(N = 6)
IgE (UI/mL)	87		136		180		285		276		199		235
sIgE (kU/L)	GM	%	GM	%	GM	%	GM	%	GM	%	GM	%	GM	%
Cow’s milk	3.7	69	6.6	56	5.1	60	5.2	62	1.9	53	9.5	36	52.0	33
Hen’s egg (white)	6.8	92	4.8	72	2.7	56	2.1	62	2.2	73	1.6	45	0.7	33
Phleum p.	0	0.5	12	3.1	24	6.2	50	4.9	47	24.8	54	13.8	33
Cynodon d.	0	0.5	16	1.9	20	3.5	50	4.7	40	10.1	54	4.4	33
D. pteronyssinus	0	0.4	4	0.6	8	1.1	25	1.7	33	3.9	36	8.1	33
D. farinae	0	0.4	4	1.1	8	1.6	19	1.7	33	4.0	36	5.6	33

The patients are divided into 2 groups according to the presence (group 1) or absence (group 2) of allergic respiratory diseases. Total and specific IgE were periodically performed according to the patients’ needs.

ISSN: 1824-7288