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Table 3 Comparison of patients’ clinical parameters and health-related quality of life scores according to body mass index

From: Factors influencing quality of life and disease severity in Hungarian children and young adults with cystic fibrosis

Characteristics Under 3rdBMI pc 3-25thBMI pc 25-75thBMI pc 75-97thBMI pc 95%CI for difference p-value
Number, (%) 11 (25) 11 (25) 16 (36.4) 6 (13.6)   
Age, yr ± SD 12.18 ± 3.09 10.55 ± 2.46 11.81 ± 3.02 13.17 ± 2.79 10.89-12.65 0.32
Shwachman-Kulczycki score ± SD 55.0 ± 11.18 81.82 ± 3.37 82.19 ± 7.52 90.83 ± 9.17 71.89-81.06 0.000
Pseudomonas aeruginosa positive, n (%) 9 (81.8) 4 (36.4) 7 (43.8) 1 (16.7)   0.04
Hospitalised, n (%) 9 (81.8) 4 (50) 2 (14.3) 0 (0)   0.001
FEV1 ± SD 48.45 ± 18.02 83.27 ± 16.57 89.00 ± 12.91 105.33 ± 14.03 72.23-87.09 0.000
Health-related quality of life (CFQ-R) Patients       
Physical functioning ± SD 55.18 ± 29.33 81.25 ± 11.13 80.12 ± 21.38 78.94 ± 18.81 66.56-81.12 0.02
Emotional functioning ± SD 70.08 ± 9.20 76.42 ± 12.41 79.12 ± 12.41 79.17 ± 7.28 72.69-79.67 0.19
Social limitations ± SD 68.11 ± 12.88 73.54 ± 14.85 72.47 ± 16.61 63.23 ± 13.59 65.75-74.88 0.50
Eating disturbances ± SD 68.69 ± 20.98 70.00 ± 32.31 90.97 ± 16.84 90.74 ± 10.92 73.06-87.67 0.02
Treatment burden ± SD 65.66 ± 22.47 70.00 ± 26.22 84.72 ± 12.75 81.48 ± 16.72 69.59-82.34 0.07
Body image ± SD 47.47 ± 28.15 73.33 ± 27.32 80.56 ± 22.77 87.04 ± 14.77 62.74-79.889 0.005
Respiratory symptoms ± SD 53.57 ± 21.27 74.52 ± 16.53 67.83 ± 14.50 79.76 ± 12.39 62.02-73.45 0.01
Digestive symptoms ± SD 90.00 ± 14.29 83.33 ± 22.38 81.95 ± 23.96 83.34 ± 18.26 78.04-90.75 0.80
Health-related quality of life (CFQ-R) Caregivers       
Physical functioning ± SD 46.76 ± 33.12 91.20 ± 10.60 87.26 ± 14.07 67.90 ± 2.13 66.96-85.90 0.000
Emotional functioning ± SD 76.67 ± 16.33 84.07 ± 5.72 76.95 ± 18.17 71.11 ± 13.88 73.06-83.61 0.53
Vitality ± SD 66.67 ± 16.33 76.67 ± 14.25 69.99 ± 11.55 60.00 ± 6.67 64.89-74.90 0.27
Eating disturbances ± SD 64.58 ± 31.42 74.07 ± 39.18 79.17 ± 21.47 66.67 ± 0.00 62.59-83.24 0.02
Treatment burden ± SD 44.45 ± 19.70 64.19 ± 14.46 65.74 ± 18.02 70.37 ± 42.07 52.67-68.16 0.10
Body image ± SD 61.11 ± 26.56 76.54 ± 23.20 85.19 ± 19.15 68.52 ± 27.40 66.56-83.79 0.16
Weight ± SD 29.17 ± 37.53 40.74 ± 32.39 86.11 ± 17.16 100.0 ± 0.00 46.62-74.22 0.000
School performance ± SD 66.67 ± 30.86 86.42 ± 17.37 77.77 ± 23.69 85.19 ± 25.66 69.34-86.91 0.39
Health perception ± SD 50.00 ± 31.43 69.14 ± 22.07 70.37 ± 19.73 70.37 ± 16.97 56.23-73.63 0.26
Respiratory symptoms ± SD 58.13 ± 21.81 79.80 ± 18.01 80.89 ± 10.31 79.889 ± 19.14 68.01-81.45 0.03
Digestive symptoms ± SD 75.00 ± 19.47 74.69 ± 13.92 63.89 ± 15.80 70.37 ± 23.13 64.22-76.41 0.42
  1. BMI = Body Mass Index, pc = Percentile, CI = Confidence Interval, PA = Pseudomonas aeruginosa, FEV1 = Forced Expiratory Volume in 1 second, CFQ-R = The Cystic Fibrosis Questionnaire Revised.