Table 2 Vasculitis: diagnosis

• clinical sympthoms: are not specific (fever, myalgia, fatigue, asthenia, bone and joint pain, weight loss) at the onset

• laboratory tests: are not specific tests expept cANCA in Wegner disease and pANCA in microscopic polyangioitis; Ag factor VIII Won Willebrand, soluble selectins, show endothelial damage of the blood vessels

• instrumental tests: echocardiogram “coronary dilatation typical of KD” also foundins JIA; MRI angiography alternative “safe” for TA diagnosis but not for the studyof small caliber vasculitis

• histo-pathological examination: it may help in the diagnostic confirmation