Table 2 Variables of our patient at the time of admission to our hospital, when he started the second line therapy with Sirolimus and after three months since the begging of this therapy
Variables | Reference range, age and sex-adjusted | Admission | Start SIROLIMUS | 3 months after SIROLIMUS |
|---|---|---|---|---|
White-cell count — per mm 3 | 4.5 - 13.5 | 15.01 | 4.04 | 5.01 |
Hemoglobin — g/dl | 11.5 - 14.5 | 16.3 | 11.7 | 11.5 |
Hematocrit —% | 35 - 42 | 46.0 | 34.4 | 35.7 |
Differential count —% | ||||
Neutrophils | 40.0 - 74.0 | 89.6 | 51.2 | 48.0 |
Lymphocytes | 19.0 - 48.0 | 6.6 | 30.3 | 38.0 |
Monocytes | 3.0 - 9.0 | 2.4 | 13.5 | 7.6 |
Eosinophils | 0.0 - 6.0 | 0.4 | 1.7 | 4.4 |
Basophils | 0.0 - 1.5 | 0.3 | 1.1 | 0.7 |
Platelet count — per mm 3 | 250 - 550 | 522 | 247 | 273 |
Glucose — mg/dl | 60 - 100 | 125 | 107 | 77 |
Insulinemia — microU/mL | 7 - 24 | 6.8 | ||
C-peptide — ng/mL | 1.1 - 4.4 | 2.7 | ||
Islet cell autoantibodies | Neg | Neg | Neg | |
Glutamic acid decarboxylase— UI/ml | <10 Neg | Neg | Neg | |
>10 Pos | ||||
UREA — mg/dl | 15 - 50 | 72 | 40 | 18 |
Creatinine — mg/dl | 0.5 - 1 | 0.91 | 0.54 | 0.35 |
Uric Ac. — mg/dl | 2.2 - 6.6 | 8.6 | 5.2 | 3.4 |
Total Colesterol — mg/dl | 130 - 204 | 121 | ||
TG — mg/dl | 31 - 108 | 40 | ||
HDL — mg/dl | > 35 | 62 | ||
LDL — mg/dl | < 170 | 50 | ||
Electrolytes — mmol/L | ||||
Sodium | 136 - 146 | 128 | 139 | 142 |
Potassium | 3.5 - 5.3 | 5.5 | 4.3 | 4.3 |
Chlorine | 98 - 106 | 85 | 103 | 105 |
Calcium | 8.8 - 10.8 | 9.6 | 9.3 | 9.2 |
Phosphorus — mg/dl | 2.9 - 5.4 | 7.6 | 5 | 4.4 |
Magnesium — mg/dl | 1.6 - 2.6 | 2.2 | 1.6 | 2.1 |
Plasma Osmolarity — mOsm/L | 278 - 305 | 266 | ||
Protein — g/dl | ||||
Total | 6,4 - 8.1 | 4.1 | 6.2 | 6.7 |
Albumin | 3.5 - 5 | 2.4 | 4.2 | 4.3 |
γ–Globulin —% | 11.1 - 18.8 | 10.5 | 11.4 | 13.4 |
Bilirubin — mg/dl | ||||
Total | 0.20 - 1.10 | 1.54 | 0.44 | 0.3 |
Direct/Indirect | 0.00-0.30/< 0.80 | 0.48/1.06 | 0.21/0.23 | 0.1/0.2 |
AST/ALT — U/L | < 38/< 41 | 44/34 | 16/10 | 22/17 |
Total Amylase — U/L | 30 - 100 | 50 | 60 | |
Iron — μg/dl | 53 - 119 | 47 | 52 | |
U.I.B.C./T.I.B.C. — μg/dl | 110-330/250-400 | 300/347 | 273/325 | |
Ferritin — ng/mL | 7 - 140 | 22 | 16 | |
TSH — microU/mL | 0.6 - 6.3 | 1.93 | 1.02 | |
FT3 — pg/mL | 2.5 - 5.5 | 3.6 | 4.1 | |
FT4 — pg/mL | 9.0 - 17.0 | 20.7 | 12.9 | |
ATA — UI/mL | < 115 | 23 | 16 | |
Anti TPO Ab — UI/mL | < 34 | 12 | 13 | |
ESR — mm | < 15 | 6 | 15 | 9 |
CRP — mg/dl | < 0.5 | 0.05 | 2.05 | 0.09 |
Ab anti harmonine IgG — U.A. | < 3.0 absent | >100 | ||
> 0.3 present | ||||
ANA | < 1:80 | < 1:80 | ||
AMA | < 1:40 | < 1:40 | ||
ENA | < 0,7 Neg | Neg | ||
0.7 - 1-0 Bl | ||||
> 1.0 Pos |