From: Congenital skin aplasia on the lower limb in a premature infant with ELBW - case report
Type | Short characteristic |
---|---|
I | ACC of the scalp without multiple anomalies. Autosomally dominant or sporadic |
II | ACC of the scalp with limb reduction anomalies. Autosomally dominant. |
III | ACC of the scalp associated with epidermal nevi or organ anomalies, associated with corneal opacity and delayed psychomotor development. Sporadic |
IV | ACC with underlying embryological malformations such as myelomeningocele, spinal cord dystrophy and hemangiomas in the subarachnoid space. ACC in any location, usually the scalp or the abdomen. |
V | ACC associated with fetus papyraceus and placental infarction. Defect in any location, usually symmetrical and linear. Occasionally accompanied by developmental retardation, nail dystrophy or dystrophy of finger and toe phalanges. |
VI | ACC associated with epidermolysis bullosa (EB), usually on the limbs. Bullae on the skin and mucosa with accompanying abnormalities of the nails. Inheritance depends on the EB type. |
VII | ACC located on the limbs, with no bullae and no malformations. Usually located in the shin area and on dorsal surfaces of the hands and feet. Autosomally dominant or recessive |
VIII | ACC caused by teratogens such as a virus infection (rubella, herpes simplex) or exposure to methimazole. This type usually occurs on the scalp |
IX | ACC associated with malformations, e.g. chromosome 13 trisomy or epidermal dysplasia. |