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Table 1 Laboratory findings at the time when aHUS was confirmed

From: First-line therapy in atypical hemolytic uremic syndrome: consideration on infants with a poor prognosis

 

Patient 1

Patient 2

Patient 3

Age

7 months

2 days

2 months

Gender

Male

Male

Female

Hemoglobin (g/L)

69 (120–160)

122 (100–160)

83 (120–150)

Platelet count (G/L)

26 (150–400)

65 (130–450)

28 (140–440)

LDH (U/L)

13500 (<500)

4826 (200–800)

5230 (100–300)

Creatinine (μmol/L)

316 ( <88)

182 (20–105)

98 (8,8-88)

Fragmentocytes

+

+

-

RBC transfusion (Unit)

6 times

2 times

-

Plasma therapy (number of sessions)

FFP (6)

FFP (9)

FFP (1)

Dialysis (sessions)

15

7

2

Outcome

Seizures, coma and respiratory failure, death on day 29 of hospitalization

Pulmonary edema and pneumothorax, death on day 17 of hospitalization

Cerebral edema, brain death on day 3 of hospitalization

Comorbidities

-

Patent ductus arteriosus

Colonic necrosis, coagulopathy

  1. Normal values are between brackets.