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Table 2 Summary of outcomes of selected studies

From: Early and late Iron supplementation for low birth weight infants: a meta-analysis

     Serum ferritin (ng/mL) Hemoglobin (g/dL)   
Study # 1st AU (year) Group number of evaluated subject before after before after Blood transfusion (%) Necrotizing enterocolitis (>bell stage 2)
1 Joy [17] early 46 112 ± 5 at 2 weeks of age 82 ± 5 12.9 ± 0.8 at 2 weeks of age 10.1 ± 0.4 2 (4.3%) 3/46
   late 47 113 ± 6 at 2 weeks of age 63 ± 3 13.1 ± 0.6 at 2 weeks of age 9.2 ± 0.4 7 (14.8%) 4/47
2 Sankar [18] early 22 55.7 ± 12.1 at enrollment 50.8 ± 11.5 na na 2 (9.5%) 1/21
   late 24 59.0 ± 12.1 at enrollment 45.3 ± 11.9 3 (13.0%) 0/23
3 Arnon [19] early 32 94 ± 27 at 2 weeks of age 46 ± 20 at 8 weeks of age 12.5 ± 0.9 at 2 weeks of age 9.0 ± 1 at 8 weeks of age 1/33 (2.8%) 1/32
   late 36 90 ± 21 at 2 weeks of age 30 ± 12 at 8 weeks of age 11.9 ± 1.3 at 2 weeks of age 7.4 ± 0.7 at 8 weeks of age 10/46 (21.3%) 3/36
4 Franz [21] early 68 85.5 (18, 282) *at birth 87.8 (9, 478)* na na 41/105 (39.0%) 6/105
   late 65 77.9 (13, 354)*at birth 74.2 (9, 682)* 53/99 (53.5%) 8/99
5 Jansson [20] early 15 102 (34–220)*at 1–2 days of age 56 (16–175)* at 8–10 weeks of age 26 (18–45)* at 6 months of age 20.0 ± 2.7 at birth 10.3 ± 1.0 at 8–10 weeks of age; 11.5 ± 0.7 at 6 monthsof age na na
   late 13 1-2 days: 100 (45–200)*at 1–2 days of age 72 (21–170)* at 8–10 weeks of age 28 (10–115)* at 6 months of age 19.1 ± 2.9 at birth 9.7 ± 1.0 at 8–10 weeks of age 11.5 ± 0.5
at 6 months of age
  1. *mean(range).
  2. na, not available.