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Table 1 Immunological data of the patients showing decrease level of IgA, T and B lymphopenia; reduced naïve T subsets (CD4RA,CD8RA); low lymphocyte proliferation to PHA; nonprotective specific antibodies response against tetanus, after vaccination; skewed T Cell Receptor repertoire

From: Multi-drugs resistant acne rosacea in a child affected by Ataxia-Telangiectasia: successful treatment with Isotretinoin

WBC/ml   9080
Serum immunoglobulin mg/dl   
IgA   <5
IgM   187
IgG   1158
IgG1   906
IgG2   94.3
IgG3   10:01
IgG4   7.16
Lymphocyte phenotype (percentage and absolute number)   
Absolute count/ml   1260
CD3 33% 534.6
CD4 18% 291.6
 CD4RA 1.6% 25.9
 CD4RO 15.5% 251.1
CD8 11% 178.2
 CD8RA 5.6% 90.7
 CD8RO 5.2% 84.2
CD19 6% 97.2
CD16-56 50% 810
Response to mitogens (counts per min)   
PHA   19%
OKT3   48%
Response to vaccination   
Ab anti-Tet   0.1U/ml
Ab anti-PcP   50 mg/l
Ab anti-HiB   0.3 mg/l
Phenotype B   
CD22+CD27+IgD+IgM+   7.2%
CD22+CD27+IgD-IgM-   20.2%
CD22+CD27-IgD+IgM+   60.5%
CD21lowCD38NEG   28.7%
CD4+ and CD8+ TCR analysis (Spectratyping)   
CD4+ SKEWED   43%
CD8+ SKEWED   100%