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Fig. 2 | Italian Journal of Pediatrics

Fig. 2

From: The great fluid debate: saline or so-called “balanced” salt solutions?

Fig. 2

Effect of hyperchloremic metabolic acidosis on circulating K+ level. In hyperchloremic metabolic acidosis some extracellular H+ shifts into the intracellular space. Since Cl- remains largely in the extracellular fluid, a shift of K+ from the intracellular to the extracellular fluid occurs. No tendency towards hyperkalemia occurs in normochloremic metabolic acidosis, such as lactate acidosis or ketoacidosis, because organic anions enter the intracellular fluid

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