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Table 1 Characteristics of included studies

From: Efficacy of acupuncture in children with asthma: a systematic review

Author (year) Study design Patients Stage of asthma Number of patients Age years (mean ± SD) Gender M/F Intervention Acupoint(s)
Karlson and Bennicke (2013) [15] RCT Children ages 6 months to 6 years with asthma NA 64 2.8 ± 1.6 NA Acupuncture + acupressure: 10 sessions (1.5 h each) over a period of 3 months Acupuncture: LIV (liver) 2
Acupressure: LU 7, REN 17, REN 22, LI 4, PC 6, SP 6, SP 10, ST 36, ST 40, K 3, K 7, DU 14, DU 20, Dingchuan
58 2.2 ± 1.1 Control: No acupuncture None
Scheewe et al. (2011) [16] RCT Children and adolescents ages 12-17 years with bronchial asthma NA 46 Male: 14.6 ± 1.8 26/20 Acupuncture: Total of 12 sessions (30 min each) over a 4-week period Bilateral bladder 13; bilateral conception vessel 17; bilateral lung 7; plus 2-6 additional points
Female: 15.0 ± 2.1
47 Male: 13.7 ± 1.2 25/22 Control: No acupuncture None
Female: 16.2 ± 1.7
Nedeljković et al. (2008) [17] RCT Children ages 7-17 years with asthma Acute bronchial obstruction 50 11 25/25 Su Jok therapy (laser at acupuncture points in hand): Total 10 sessions (5 each week except for weekends over 12 days) According to the 6-Ki Su Jok principles
50 25/25 Control: No acupuncture None
Stockert et al. (2007) [18] RCT Children ages 6-12 years with asthma Intermittent or mild 7 9.4 ± 2.4 NA Laser acupuncture (10 treatments of laser acupuncture on a once-weekly schedule) + probiotic drops (20 drops 3 times daily for 7 weeks) Lung 1, 5, 7, 9, 11; large intestine 4, 6, 19, 20; bladder 13, 17, 18, 20, 21, 23; stomach 13, 25, 36, 40, 44; spleen 3, 6, 9, 10; heart 3, 5, 7; small intestine 3; kidney 3, 6, 8, 27; pericardium 6; triple heater 5, 15; gallbladder 3, 34, 40, 41; liver 2, 3, 8, 13; Yintang, Dingchuan; conception vessel 4, 6, 9, 17, 21; governor vessel 4, 13
9 10.0 ± 1.9 Control: 10 placebo laser acupuncture sessions + placebo drops No laser light
Gruber et al. (2002) [19] RCT, crossover Children with exercise-induced asthma Mild to moderate 44 11.9 ± 2.6 26/18 Laser acupuncture: Single treatment Yintang (EX 1), Chize (LU 5), Lieque (LU 7), Feishu (UB 13), Geshu (UB 17), and Shanzhong (CV 17)
Control: Laser acupuncture at placebo points; single treatment Baihui (GV 20), Quze (PE 3), Neiguan (PE 6), Dashu (UB 11), Weishu (UB 21), and Zhongwan (CV 12)
Fung et al. (1986) [20] RCT, crossover Children with exercise-induced asthma Mild to moderate 19 Range 9-13.5 NA Acupuncture: Applied 20 min before exercise Dingchuan (extra 17), kongzui (L6), and taixi (K3)
NA Control: No acupuncture or acupuncture applied at placebo points 20 min before exercise Placebo points: Jianwaishu (SI14), ximen (P4), and xuanzhong (G39)
Chow et al. (1983) [21] RCT, crossover Children with exercise-induced asthma NA 16 11 (range 8-13) NA Acupuncture: Applied 10 min before exercise (once per week for 2 weeks) Auricular lung point
Control: No acupuncture (baseline) or acupuncture applied at placebo point Auricular lumbago point
  1. F, female; M, male; NA, not available/applicable; RCT, randomized controlled trial; SD, standard deviation