Table 1 Main clinical variables in the two studied groups
G1 | G2 | p | ||
|---|---|---|---|---|
N = 59 | N = 45 | |||
Female | (n - %) | 40 – 67.8 | 22 – 48.9 | 0.07 |
Twins | (n - %) | 12 – 20.3 | 15 – 33.3 | 0.176 |
Gestational age | (M ± SD) wk | 28.1 ± 1.7 | 28.3 ± 1.2 | 0.591 |
Birth weight | (M ± SD) g | 1110.8 ± 304.6 | 1099.8 ± 229.0 | 0.840 |
Vaginal delivery | (n - %) | 7 – 11.9 | 3 – 6.7 | 0.508 |
5’ Apgar score >7 | (n - %) | 56 – 94.9 | 42 -93.3 | 1.000 |
Prenatal steroid treatment (n - %) | 31 – 52.5 | 26 – 57.8 | 0.692 | |
Postnatal steroid treatment | ||||
n - % | 8 – 13.6 | 6 – 13.3 | 1.000 | |
M ± SD, d | 0.9 ± 2.4 | 1.9 ± 8.2 | 0.361 | |
Surfactant treatment (n - %) | 56 – 94.9 | 28 – 62.2 | <0.01 | |
CPAP (M ± SD), h | 319.4 ± 311.4 | 274.4 ± 221.4 | 0.412 | |
Conventional mechanical ventilation, (M ± SD), h | 80.7 ± 121.2 | 60.0 ± 104.4 | 0.361 | |
HFOV (M ± SD), h | 54.8 ± 139.8 | 22.8 ± 92.7 | 0.187 | |
O2 therapy (M ± SD), h | 281.5 ± 395.1 | 330.0 ± 443.1 | 0.558 | |
Inhaled nitric oxide(M ± SD), h | 2.8 ± 15.5 | 3.9 ± 15.5 | 0.708 | |
Bronchopulmonary dysplasia (n - %) | 32 – 54.2 | 18 – 40.0 | 0.169 | |
Indomethacin treatment (n - %) | 7 – 11.9 | 1 – 2.2 | 0.133 | |
Patent ductus arteriosus ligation (n - %) | 4 – 6.8 | 0 – 0.00 | 0.131 | |
Packed red blood cells transfusions | ||||
n - % | 36 – 61.0 | 31 – 68.9 | 0.535 | |
M ± SD | 1.4 ± 1.5 | 1.4 ± 1.5 | 0.850 | |
Retinopathy of prematurity grade I-II (n - %) | 37 – 62.7 | 20 – 44.4 | 0.075 | |
Intracranial hemorrhage grade I-II (n - %) | 22 – 37.3 | 28 – 62.2 | 0.017 | |
Intracranial hemorrhage grade I (n - %) | 6 – 10.2 | 6 – 13.3 | 0.759 | |
Intracranial hemorrhage grade II (n - %) | 16 – 27.1 | 22 – 48.9 | 0.026 | |
Necrotizing enterocolitis (n - %) | 1 – 1.7 | 0 – 0.0 | 1.000 | |