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Table 2 Baseline patient characteristics

From: The effects of selective head cooling versus whole-body cooling on some neural and inflammatory biomarkers: a randomized controlled pilot study

  SHC (n = 14) WBC (n = 10) Mild HIE (n = 7) Control (n = 9) P
Gestational age (weeks) 38.6 ± 1.1 38.9 ± 1.0 38.8 ± 1.1 38.8 ± 0.8 0.931
Birth weight (g) 3183 ± 501 3218 ± 445 3410 ± 306 3081 ± 289 0.480
Head circumference (cm) 34.7 ± 1.1 34.7 ± 0.7 34.5 ± 1.0 34.6 ± 0.6 0.945
Male 4 (28.6) 3 (30.0) 2 (28.6) 4 (44.4) 0.905
Delivery via cesarean section 2 (14.3) 4 (40.0) 2 (28.6) 3 (33.3) 0.512
Birth in the treatment center 1 (7.1) a 0 (0.0) a 0 (0.0) a 7 (77.8) b <0.001
Age at group randomization (h) 5.4 ± 1.6 5.9 ± 0.3 5.3 ± 1.1 4.6 ± 1.9 0.225
Rectal temperature at group randomization (°C) 34.1 ± 0.9 34.4 ± 1.3 NA NA 0.615
Existence of clinical convulsions 13 (92.9) a 9 (90.0) a 0 (0.0) b 0 (0.0) b <0.001
Invasive mechanical ventilation 13 (92.9) a 9 (90.0) a 2 (28.6) b 0 (0.0) b <0.001
5-min Apgar score (n = 35)
 0–3 5 (50.0) 4 (40.0) 0 (0.0) 0 (0.0)  
 4–6 5 (50.0) 6 (60.0) 5 (83.3) 0 (0.0)
 7–10 0 (0.0) 0 (0.0) 1 (16.7) 9 (100)
10-min Apgar score (n = 24)
 0–3 1 (14.3) 3 (75.0) 0 (0.0) 0 (0.0)  
 4–6 6 (85.7) 1 (25.0) 1 (25.0) 0 (0.0)
 7–10 0 (0.0) 0 (0.0) 3 (75) 9 (100)
Blood gas analysis within 1 h post birth
 pH 6.9 ± 0.2a 7.0 ± 0.1a 7.0 ± 0.1a 7.30 ± 0.1b 0.001
 Base excess (mmol L−1) −17.7 ± 2.9a −19.6 ± 1.2a −17.8 ± 8.9a −2.6 ± 1.3b <0.001
aEEG before randomization
 Normal 0 (0.0) 0 (0.0) 7 (100) NA <0.001
 Moderate abnormality 3 (21.4) 1 (10.0) 0 (0.0) NA
 Severe abnormality 11 (78.6) 9 (90.0) 0 (0.0) NA
Sarnat stage
 Stage I 0 (0.0) 0 (0.0) 7 (100) NA <0.001
 Stage II 3 (21.4) 1 (10.0) 0 (0.0) NA
 Stage III 11 (78.6) 9 (90.0) 0 (0.0) NA
  1. Values are given as median ± SD, or number of patients and percentage
  2. a and b denote differences between groups, according to post hoc test. There is a significant difference data shown with different letters (P < 0.05)