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Table 3 Biomarker levels at 6 h

From: The effects of selective head cooling versus whole-body cooling on some neural and inflammatory biomarkers: a randomized controlled pilot study

Biomarkers SHC group (n = 14) WBC group (n = 10) Mild HIE group (n = 7) Control group (n = 9)
IL-6 (pg mL−1) 49.5a (15.8–219.9) 46.7a (33.1–413.5) 24.7a,b (14.0–69.6) 3.8b (2.8–6.6)
IL-1β (pg mL−1) 2.2 (2.1–2.3) 2.5 (2.1–3.0) 2.1 (2.0–2.6) 2.1 (2.0–2.2)
TNF-α (pg mL−1) 15.2 (10.8–25.6) 15.8 (13.7–41.6) 20.3 (13.9–25.6) 15.3 (13.1–24.4)
NSE (μg L−1) 0.58 (0.44–1.62) 0.67 (0.48–2.65) 0.49 (0.37–2.13) 0.45 (0.36–0.51)
S100B (ng mL−1) 0.08 (0.07–0.09) 0.12 (0.07–0.15) 0.11 (0.08–0.15) 0.07 (0.06–0.08)
S100 (ng L−1) 17.5a (5.6–60.4) 15.3a (7.7–86.9) 1.7a,b (0.8–25.6) 1.9b (0.7–4.7)
CKBB (ng mL−1) 1.9 (1.5–3.0) 2.1 (1.4–3.9) 1.9 (1.4–2.3) 1.4 (1.1–1.8)
L/C ratio 9.24a (1.32–43.89) 3.00a (0.82–34.60) 0.05b (0.03–0.11) 0.04b (0.03–0.08)
  1. Data shown as median (IQR)
  2. a and b denote differences between groups, according to post hoc test. There is a significant difference data shown with different letters (P < 0.05)