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Table 4 Biomarker levels at 72 h

From: The effects of selective head cooling versus whole-body cooling on some neural and inflammatory biomarkers: a randomized controlled pilot study

Biomarkers SHC group (n = 14) WBC group (n = 10) Mild HIE group (n = 7) Control group (n = 9)
IL-6 (pg mL−1) 64.2a (30.4–118.0) 43.0a (33.1–416.0) 4.3b (1.2–17.6) 3.0b (1.3–6.0)
IL-1β (pg mL−1) 2.2 (2.0–2.3) 2.2 (2.1–2.6) 2.3 (2.1–2.7) 2.1 (2.0–2.2)
TNF-α (pg mL−1) 19.5 (12.5–41.7) 17.0 (13.3–25.3) 24.3 (20.2–40.6) 15.7 (10.8–16.7)
NSE (μg L−1) 0.51 (0.38–0.74) 0.57 (0.38–1.70) 1.01 (0.40–1.93) 0.38 (0.32–0.47)
S100B (ng/ml 0.08 (0.07–0.15) 0.10 (0.06–0.15) 0.12 (0.07–0.21) 0.08 (0.07–0.12)
S100 (ng L−1) 2.9 (0.5–15.5) 9.5 (0.3–29.8) 1.6 (0.8–3.6) 1.5 (0.4–3.8)
CKBB (ng mL−1) 1.0 (0.6–1.7) 0.8 (0.5–1.5) 0.9 (0.7–1.1) 1.0 (0.8–1.1)
L/C ratio 0.08 (0.04–0.27) 0.06 (0.04–0.16) 0.05 (0.03–0.06) 0.03 (0.02–0.04)
  1. Data shown as median (IQR)
  2. a and b denote differences between groups, according to post hoc test. There is a significant difference data shown with different letters (P < 0.05)