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Table 5 The relationship between biomarker levels at 6 h and outcomes at age 12 months

From: The effects of selective head cooling versus whole-body cooling on some neural and inflammatory biomarkers: a randomized controlled pilot study

Biomarkers

Patients with adverse outcomes (n = 18)

Patients with favorable outcomes (n = 13)

IL-6 (pg mL−1)

121.1 (31.4–334.3)*

33.2 (13.0–61.7)

IL-1β (pg mL−1)

2.3 (2.1–2.5)

2.3 (2.0–2.5)

TNF-α (pg mL−1)

16.6 (10.8–32.7)

16.5 (13.3–21.0)

NSE (μg L−1)

0.55 (0.44–1.10)

1.31 (0.46–2.15)

S100B (ng mL−1)

0.08 (0.06–0.13)

0.08 (0.07–0.15)

S100 (ng L−1)

13.5 (5.8–31.0)

22.4 (1.3–136.4)

CKBB (ng mL−1)

2.1 (1.5–3.5)

1.9 (1.4–2.4)

L/C ratio

19.0 (2.64–47.89)*

0.12 (0.04–0.36)

  1. Data shown as median (IQR)
  2. *There is a significant difference between groups (P < 0.05)