The effects of selective head cooling versus whole-body cooling on some neural and inflammatory biomarkers: a randomized controlled pilot study

Table 6 The relationship between biomarker levels at 72 h and outcomes at age 12 months

Biomarkers	Patients with adverse outcomes (n = 18)	Patients with favorable outcomes (n = 13)
IL-6 (pg mL⁻¹)	60.3 (29.1–121.1)*	24.6 (3.9–45.0)
IL-1β (pg mL⁻¹)	2.1 (2.0–2.2)	2.3 (2.1–2.7)
TNF-α (pg mL⁻¹)	17.7 (12.2–41.3)	22.8 (15.7–31.9)
NSE (μg L⁻¹)	0.52 (0.38–0.74)	0.98 (0.44–2.13)
S100B (ng mL⁻¹)	0.09 (0.06–0.12)	0.11 (0.07–0.21)
S100 (ng L⁻¹)	1.9 (0.4–15.8)	3.5 (0.7–20.1)
CKBB (ng mL⁻¹)	0.8 (0.6–1.5)	1.0 (0.7–1.3)
L/C ratio	0.13 (0.04–0.26)*	0.04 (0.03–0.06)

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